Results 221 to 230 of about 831,247 (334)

Natural Antioxidants in Salmon Aquaculture: Processing Fate, Tissue Deposition, and Oxidative Protection. [PDF]

Aquac Nutr
Araujo P, Sarmiento V, Elvebø O, Heavyside R, Ødegård E, Sharma S, Hamre K.   +6 more
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The potential of immature jackfruit in meat analogues. [PDF]

Curr Res Food Sci
Swinkels ACM, Schutyser MAI, van der Goot AJ.   +2 more
europepmc   +1 more source

Active Herbicide Ingredients in Roundup Ready Xtend Products, Glyphosate and Dicamba, Results in Hypoactivity in Zebrafish Larvae When Exposed During Development

Ryker Bond
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Key genes of Taohong Siwu decoction in treating coronary heart disease based on network pharmacology and Mendelian randomization. [PDF]

Medicine (Baltimore)
Wang C, Li X, Wang J.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Design of a Nutraceutical Gummy Candy Incorporating Hydrolysed Hemp (<i>Cannabis sativa</i> L.) as an Antioxidant and Antihypertensive Ingredient. [PDF]

Bioengineering (Basel)
Bastardo Á, Jiménez-Pulido IJ, Ordás E, Rico D, Aparicio N, Arjona JM, Martín-Diana AB.   +6 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Determination of IR3535 in Topical Insect Repellents: A New HPLC-DAD Analytical Approach and Compliance Assessment. [PDF]

Biomed Chromatogr
Farias FF, Bárbara MCS, Andreo-Filho N, Lopes PS, Silva MSG, Silva VCM, Leite-Silva VR.   +6 more
europepmc   +1 more source