Results 21 to 30 of about 2,456,442 (305)
Tyrosinase Inhibition Ability Provided by Hop Tannins: A Mechanistic Investigation
Biology and Life Sciences Forum, 2021 The hop is rich in tannins used as a conventional additive in the beer industry, but other applications are limited. This study investigated the tyrosinase inhibition activity of extracted hop tannins and the associated structure–function activity.
Jiaman Liu +6 more
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Molecules, 2022 Viniferifuran was investigated for its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme catalyzing xanthine to uric acid. An enzyme kinetics analysis showed that viniferifuran possessed a strong inhibition on XO in a typical anti ...
Yaxin Yang +4 more
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Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract. [PDF]
, 2006 Anthocyanins are natural colorant belonging to the flavonoid family, widely distributed among flowers, fruits, and vegetables. Some flavonoids have been found to possess anticarcinogenic, cytotoxic, cytostatic, antioxidant, and anti-inflammatory ...
CUZZOCREA S +4 more
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THE MECHANISM OF THE INHIBITION OF HEMOLYSIS [PDF]
Journal of General Physiology, 1943 1. When digitonin is the lysin, the inhibitory power of sols of cholesterol and related substances depends primarily on a normal, as opposed to an epi, configuration of H and OH at C3. Subsidiary inhibitory effects depend on whether the double bond of cholesterol at C5 is saturated or not, and a trans hydrogen at C5 is associated with a greater ...
openaire +6 more sources
Ferroptosis Inhibition: Mechanisms and Opportunities
Trends in Pharmacological Sciences, 2017 The past decade has yielded tremendous insights into how cells die. This has come with our understanding that several distinct forms of cell death are encompassed under the umbrella term necrosis. Among these distinct forms of regulated necrotic cell death, ferroptosis has attracted considerable attention owing to its putative involvement in diverse ...
Friedmann Angeli, J.P.F. +3 more
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Toxins, 2022 Microcystins (MCs) exhibit diversified inhibition effects on protein phosphatases (PPs) due to their structural differences. To fully evaluate the potential mechanism for the discrepant inhibition effects, the five most frequent MCs with varying residues
Yixue Xu +3 more
doaj +1 more source
Journal of Fungi, 2023 Purpose: This study aimed to identify the antagonistic bacteria from the rhizosphere of healthy bananas that can effectively suppress the Fusarium wilt of banana, and to further investigate the inhibitory mechanism.
Yajie Duan +5 more
doaj +1 more source
JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. [PDF]
, 2009 Background: cJun terminal kinase (JNK) is constitutively activated in most hepatocellular carcinomas (HCCs), yet its exact role in carcinogenesis remains controversial.
Bruns, Christiane +10 more
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Basic Mechanisms of JAK Inhibition
Mediterranean Journal of Rheumatology, 2020 Over recent decades, treatment options for inflammatory diseases such as rheumatoid arthritis (RA) have increased dramatically. These range from orally available steroids and conventional synthetic disease modifying drugs (csDMARDs) to parenteral biological therapies (bDMARDs).
Lin, Chung MA +2 more
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Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma [PDF]
, 2016 Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. We previously showed that the inhibition of placental growth factor (PlGF) exerts antitumour effects and induces vessel normalisation, possibly reducing hypoxia ...
Bogaerts, Eliene +13 more
core +1 more source