Results 211 to 220 of about 166,084,760 (290)

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

Genistein from Thai Fermented Soybean (Thua-nao) Attenuates Osteoarthritis Pathogenesis via Dual Inhibition of NF-κB and MAPK Signaling: Evidence from Ex Vivo, Computational, and In Vitro Models. [PDF]

J Agric Food Chem
Wudtiwai B, Chongchai A, Sittiju P, Wayupat A, Chuntakaruk H, Chewonarin T, Ruangsuriya J, Kongtawelert P, Phitak T, Pothacharoen P.   +9 more
europepmc   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Biomarkers of pulmonary fibrosis in bronchoalveolar lavage fluid and saliva. Study methods and pathophysiological significance. [PDF]

Front Med (Lausanne)
Ángel-Reimúndez C, Ruibal-Caballero MF, Leiro-Fernández V, Salgado-Arteta M, González-Matías LC, Fernández-Villar A, Mallo F.   +6 more
europepmc   +1 more source

Matrix Metalloproteinases and Cardiac Remodelling in Smokers with Acute Coronary Syndrome. [PDF]

Int J Mol Sci
Aminuddin A, Samah N, Nor FM, Wan Razali WMH, Cong BB, Mohamad SF, Hamid AA, Norhisham WK, Ugusman A.   +8 more
europepmc   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Histological features of <i>Jaculus jaculus</i> male-reproductive system: detection of metalloproteinases in testes and seminal vesicles during the active-reproductive phase. [PDF]

Anim Reprod
Zeghloul N, Lebaili-Benmoussa N, Ousmaal MEF, Lamine S, Gharnaout NL, Lekmine S, Moula N, Elfalleh W, Boufahja F, Bendif H, Tahraoui H, Amrane A.   +11 more
europepmc   +1 more source

Optimising the Eco‐Friendly Extraction of Carotenoids From Gac Fruit: A Sustainable Solution for Natural Red Food Colourants

Food Chemistry International, EarlyView.
Gac fruit's high carotenoid content, especially in the aril, makes it an excellent natural red pigment source for food applications, offering a safer alternative to synthetic dyes. Ethanol extraction achieved the highest overall pigment recovery (89.53%), whereas ethyl lactate extraction yielded the highest levels of total carotenoids, β‐carotene ...
N. Netravati, S. Gomez, B. Pathrose, A. Suma, J. Hosamani   +4 more
wiley   +1 more source

From sebocytes to skin engineering human sebaceous organoids within a reconstructed dermal matrix. [PDF]

Front Toxicol
Pusceddu T, Ardondi L, Cavaleri MP, Sileo L, Vitali I, Meza CQ, Massironi M, Massironi M, Zavan B.   +8 more
europepmc   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source