Results 31 to 40 of about 166,084,760 (290)

Content of matrix metalloproteinases in the blood of hypertensive patients with a high cardiovascular risk receiving statin therapy

open access: yesКардиоваскулярная терапия и профилактика, 2022
Aim. To compare the effect of atorvastatin and rosuvastatin as part of complex therapy in patients with hypertension (HTN) with a high cardiovascular risk on the level of matrix metalloproteinases -1, -9 (MMP-1, MMP-9) and tissue inhibitors of ...
V. P. Mikhin   +4 more
doaj   +1 more source

Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1 [PDF]

open access: yes, 2000
Bachmeier BE, Nerlich AG, Boukamp P, et al. Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1. BIOLOGICAL CHEMISTRY.
Boukamp, P   +13 more
core   +1 more source

Role of matrix metalloproteinases in diabetic foot ulcers: Potential therapeutic targets

open access: yesFrontiers in Pharmacology, 2022
Diabetic foot ulcers (DFUs) are pathological states of tissue destruction of the foot or lower extremity in diabetic patients and are one of the serious chronic complications of diabetes mellitus.
Kang Fu   +11 more
doaj   +1 more source

Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]

open access: yes, 2001
Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Nelson, EL   +17 more
core   +1 more source

Changes in the extracellular matrix under the influence of anticoagulant therapy in patients with Q-myocardial infarction after thrombolysis

open access: yesZaporožskij Medicinskij Žurnal, 2014
Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
doaj   +1 more source

MMPs and TIMPs expression in facial tissue of children with cleft lip and palate

open access: yesBiomedical Papers, 2016
Background and Aims: Morphogenesis of the upper lip and palate is a complex process involving highly regulated interactions between epithelial and mesenchymal cells.
Liene Smane-Filipova   +2 more
doaj   +1 more source

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

open access: yes, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Elfriede Noessner   +43 more
core   +2 more sources

Gender peculiarities and prognostic value of matrix metalloproteinase and their inhibitors system in patients with acute Q-wave left ventricle myocardial infarction

open access: yesZaporožskij Medicinskij Žurnal, 2015
Matrix metalloproteinases play a key role in postinfarction remodeling of the heart. The aim was to study gender and age peculiarities of matrix metalloproteinases and their inhibitors, and determine their prognostic value in post-infarction aneurysm ...
S. M. Kyselov
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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