ABSTRACT Plant viruses drive widespread crop epidemics, yet the host plant responses across different cell types, particularly how these responses are influenced by cultivars with varying genetic backgrounds, including the presence of resistance (R) genes, remain poorly understood. Using tomato brown rugose fruit virus (ToBRFV) and two tomato cultivars,
Yuhong Zhang +8 more
wiley +1 more source
Targeting Pathways Implicated in Cholesterol Metabolism for Novel Cancer Therapy. [PDF]
Zhou Y +15 more
europepmc +1 more source
SUMMARY Plasma membranes (PM) contain myriads of diverse nanodomains that correspond to nanometric scale structures enriched in specific lipids and proteins acting as signaling/regulation hubs involved in diverse biological processes. So far, how PM nanodomains are formed and maintained in plant cells remains largely unknown.
Michal Daněk +18 more
wiley +1 more source
Sterol Endoperoxides and Their Antileishmanial Effects: Influence on Viability, Oxygen Metabolism and Sterol Synthesis. [PDF]
Sarkar D +11 more
europepmc +1 more source
Processing and release of endogenous immunogenic peptide signals
SUMMARY In both animals and plants, small secreted peptides known as cytokines and phytocytokines mediate local and systemic communication during immune and stress responses. These signaling molecules are typically synthesized as inactive precursors that require proteolytic processing to become active.
Maurice Koenig +3 more
wiley +1 more source
Transcriptomic Insights into Sre1-Related Regulatory Responses to Hypoxia, Cobalt Chloride, and Clotrimazole in <i>Phaffia rhodozyma</i>. [PDF]
Baeza M +3 more
europepmc +1 more source
Advances and opportunities for computational interrogation of plant proteins
SUMMARY Plants exhibit remarkable biochemical and physiological diversity, and are capable of adapting to a wide range of environmental conditions and stresses. This complexity makes them essential systems for understanding how life responds to a changing climate.
Sarah M. Bohling +2 more
wiley +1 more source
Regulation of sterol metabolism by gut microbiota and its relevance to disease. [PDF]
Huang C +7 more
europepmc +1 more source
The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches. [PDF]
Mavridi D, Katavati T, Kourounakis AP.
europepmc +1 more source
Revisiting cholesterol metabolism in hepatocellular carcinoma: a hidden driver of systemic therapy response. [PDF]
Stoffels LM +3 more
europepmc +1 more source

