Results 141 to 150 of about 32,395 (260)

Hepatitis C Virus and Type 2 Diabetes: Mechanisms, Clinical Impact, and Post‐DAA Management

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Hepatitis C virus (HCV) infection remains a major global health burden despite advances in direct‐acting antiviral (DAA) therapies. Beyond hepatic complications such as cirrhosis and hepatocellular carcinoma (HCC), HCV has been strongly linked to metabolic disorders, particularly type 2 diabetes mellitus (T2DM).
Shen‐Shong Chang, Ching‐Hsuan Liu, Shu‐Yen Chan, Liang‐Tzung Lin   +3 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

Organ‐Specific Phytochemical Composition and Bioactivity Profiling of Chaerophyllum aksekiense: A Multiassay Antioxidant, Enzyme Inhibition, and Correlation‐Based Evaluation

ChemistryOpen, Volume 15, Issue 5, May 2026.
This study reveals the organ‐specific phytochemical specialization of the endemic Chaerophyllum aksekiense for the first time. Although leaves exhibit the highest phenolic content and antioxidant capacity, flowers stand out with flavonoid accumulation, and roots demonstrate potent enzyme inhibition.
Bedrettin Selvi, Elif Aktürk Bozdemir
wiley   +1 more source

Steroidal allenes as inhibitors of sterol biosynthesis

Steroidal allenes as inhibitors of sterol biosynthesis
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

From flower buds to bolls: how cotton reproductive structures shape boll weevil development, reproduction and survival

Pest Management Science, Volume 82, Issue 5, Page 4576-4584, May 2026.
Female boll weevils feeding on flower buds promote reproduction regardless of their immature diet, whereas boll feeding increases lipid reserves and lifespan, revealing a nutrition‐driven trade‐off that sustains survival and reproduction in tropical boll weevil populations.
Roberta Ramos Coelho, Guilherme Gomes Rolim, Franklin Magliano da Cunha, Valéria Wanderley‐Teixeira, José Dijair Antonino, Jorge Braz Torres   +5 more
wiley   +1 more source

Advances in Wine Yeast Autolysis: Biochemical and Molecular Mechanisms, and the Release of Organic Compounds in White and Sparkling Wines—An Updated Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos, Aniela Pinto Kempka   +1 more
wiley   +1 more source

Sphingolipid synthesis is necessary for kinetoplast segregation and cytokinesis in Trypanosoma brucei [PDF]

, 2008
Almeida, Igor C., Engman, David M., Fridberg, Alina, Nakayasu, Ernesto S., Olson, Cheryl L., Tyler, Kevin M.   +5 more
core   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Inferring Gene Regulatory Network Architecture Underlying Complex Traits: An Integrative Analysis of Mutant Lifespan and Gene Expression Profiles Identifies Master Regulators and Key Functional Modules for Yeast Aging

Aging Cell, Volume 25, Issue 5, May 2026.
We developed a LASSO‐based approach to uncover a three‐layered “fan‐in fan‐out” network architecture for complex traits like yeast aging, showing that peripheral genes influence lifespan indirectly through master regulators, which converge on core functional modules (e.g., stress response, autophagy).
Meng Ma, Juan Long, Yuting Chen, Yanqiu Shao, Man Zhu, Jiashun Zheng, Lu Yang, Yin Xiao, Matt Kaeberlein, Brian K. Kennedy, Yi Zheng, Hao Li, Jing Yang   +12 more
wiley   +1 more source

A mitochondrial machinery for membrane translocation of precursor proteins [PDF]

, 1990
Neupert, Walter, Pfanner, Nikolaus
core   +1 more source