Results 141 to 150 of about 17,106 (263)

Effects of various oxygenated sterols on cellular sterol biosynthesis in Chinese hamster lung cells resistant to 25-hydroxycholesterol.

, 1979
The effects of a wide variety of oxygenated sterols upon sterol biosynthesis and hydroxymethylglutaryl-CoA reductase (mevalonate: NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34) activity in a wild-type clone and in a 25-hydroxycholesterol-resistant
Kandutsch, A A, Chen, H W, Cavenee, W K, Gibbons, G F   +3 more
core  

The Chemical Structures, Neuroprotective Effects, Structure–Activity Relationships, and Applications of Flavonoids, Phenolic Acids, Terpenoids, and Sterols in Dandelion: A Review

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This review systematically summarizes the chemical structures and structure–activity relationships of key bioactive compounds in dandelion, including flavonoids, phenolic acids, terpenoids, and sterols. It highlights their neuroprotective mechanisms against neuroinflammation and oxidative stress, while outlining their promising dual applications in the
Hongye Li, Bingchan Qu, Jiasu Wu, Menghan Sun, Youlin Xue, Tiejing Li, Chang Tan, Shan Wang, Chong Ning, Chongting Guo   +9 more
wiley   +1 more source

Molecular Characterization of Sterol C4-Methyl Oxidase in Leishmania major

© 2024 by the authors. NoneSterol biosynthesis requires the oxidative removal of two methyl groups from the C-4 position by sterol C-4-demethylase and one methyl group from the C-14 position by sterol C-14-demethylase. In Leishmania donovani, a CYP5122A1
Yu Ning, Mei Feng, Hsu, Fong Fu, Fong-fu Hsu, Wang, Michael Zhuo, Zhang, Kai, Basu, Somrita, Kai Zhang, Ning, Yu, Hsu, Fong-Fu, Somrita Basu, Feng, Mei, Michael Zhuo Wang   +12 more
core   +1 more source

Safflower (Carthamus tinctorius L.) Seed Oils: Effect of Extraction Process and Cultivars on Chemical Composition, Physicochemical Parameters and Nutritional Quality Index

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
M. pulegium essential oil study emphasizes molecular structure analysis and bioactivity. Chemical composition varies based on geographical origin. In silico analyses confirm binding affinities. Essential oil shows potent insecticidal activity with LD50 and LT50.
Chaimae El Kourchi, Oumayma Belhoussaine, Rim Mohammed Ali, Mohammed Amakhmakh, Khalid M. Sumaily, Agnese Santanatoglia, Filippo Maggi, Giovanni Caprioli, Abdelhakim Bouyahya, Mohamed Tabyaouı, Hicham Harhar   +10 more
wiley   +1 more source

Enteromorpha prolifera Polysaccharide Alleviates Type 2 Diabetes via the Gut Microbiota–Liver Axis to Modulate Cholesterol Metabolism

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Enteromorpha prolifera polysaccharides may help restore lipid metabolism homeostasis by gently remodeling the gut microbiota to enrich beneficial bacteria and SCFAs, which in turn appears to modulate hepatic functions through the portal vein by downregulating cholesterol synthesis and promoting its metabolism. This coordinated process potentially leads
Liuying Zhu, Xusheng Wen, Wenrong Zhu, Xueqian Hu, Yanqun Xu, Xin Peng   +5 more
wiley   +1 more source

Macrophage signaling and function are regulated by distinct sterol biochemistries. [PDF]

J Lipid Res
Yaeger JDW, Pradhan B, Kerkvliet JG, Lawver AG, Sengupta S, Thiex NW, Francis KR.   +6 more
europepmc   +1 more source

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review). [PDF]

Oncol Rep
Liu Q, Wang R, Li Z, Liu Y, Wu L, Zhao Y, Yang J.   +6 more
europepmc   +1 more source

Sterol biosynthesis inhibitors

Biomedicine & Pharmacotherapy, 1989
openaire   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

The potential of metabolic engineering for sustainable phytosterol production. [PDF]

Adv Biotechnol (Singap)
Hu R, Di X, Li G, Schaller H, Hemmerlin A, Liao P.   +5 more
europepmc   +1 more source