Results 31 to 40 of about 17,106 (263)

Sterol Metabolism Differentially Contributes to Maintenance and Exit of Quiescence

open access: yesFrontiers in Cell and Developmental Biology, 2022
Nutrient starvation initiates cell cycle exit and entry into quiescence, a reversible, non-proliferative state characterized by stress tolerance, longevity and large-scale remodeling of subcellular structures.
Carlotta Peselj   +11 more
doaj   +1 more source

Microbial Test-System for Screening of Inhibitors of Sterol Biosynthesis

open access: yesАнтибиотики и Химиотерапия, 2020
New effective economic microbial test-system for screening of microbial metabolites, that are inhibitors of sterol biosynthesis, is proposed. It is based on cultivation of fungal strain Acremonium fusidioides (former Fusidium coccineum), that produces ...
A. S. Trenin
doaj  

Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum. [PDF]

open access: yesPLoS ONE, 2017
The sterol regulatory element binding proteins (SREBPs) are key regulators for sterol homeostasis in most fungi. In the citrus postharvest pathogen Penicillium digitatum, the SREBP homolog is required for fungicide resistance and regulation of CYP51 ...
Ruoxin Ruan   +5 more
doaj   +1 more source

Isolation and identification of antitrypanosomal and antimycobacterial active steroids from the sponge haliclona simulans

open access: yes, 2014
The marine sponge Haliclona simulans collected from the Irish Sea yielded two new steroids: 24-vinyl-cholest-9-ene-3β,24-diol and 20-methyl-pregn-6-en-3β-ol,5a,8a-epidioxy, along with the widely distributed 24-methylenecholesterol.
Ooi, Thengtheng   +18 more
core   +1 more source

Plant Growth Retardants as Inhibitors of Sterol Biosynthesis in Tobacco Seedlings [PDF]

open access: yesPlant Physiology, 1974
Three plant-growth retardants 2'-isopropy1-4'-(trimethylammonium chloride)-5-methylphenylpiperidine carboxylate (Amo 1618), beta-chloroethyltrimethylammonium chloride, and tributyl-2, 4-dichlorobenzylphosphonium chloride were tested for their effects on sterol production in, and growth of tobacco (Nicotiana tabacum) seedlings.
T J, Douglas, L G, Paleg
openaire   +2 more sources

Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato [PDF]

open access: yes, 2007
Glycoalkaloids are secondary metabolites present within species of the family Solanaceae. They are toxic to humans and animals, and it is important to keep the levels in potato (Solanum tuberosum L.) tubers below the safe limit for consumption ...
Arnqvist, Lisa
core  

Dissecting cholesterol and phytosterol biosynthesis via mutants and inhibitors

open access: yes, 2021
Plants stand out among eukaryotes due to the large variety of sterols and sterol derivatives that they can produce. These metabolites not only serve as critical determinants of membrane structures, but also act as signaling molecules, as growth ...
Beeckman, Tom   +4 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Microbial model of Halobacterium salinarum for screening inhibitors of sterol biosynthesis

open access: yesАнтибиотики и Химиотерапия, 2020
A highly effective and simple microbial test system for screening inhibitors of sterol biosynthesis (ISB) is described. The system is based on cultivation of the bacterial strain Halobacterium salinarum (former Halobacterium halobium), that possesses ...
A. S. Trenin
doaj  

Effects of distal cholesterol biosynthesis inhibitors on cell proliferation and cell cycle progression

open access: yesJournal of Lipid Research, 2005
Cholesterol is a major lipid component of the plasma membrane in animal cells. In addition to its structural requirement, cholesterol is essential in cell proliferation and other cell processes.
Carlos Fernández   +3 more
doaj   +1 more source

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