Results 91 to 100 of about 423,721 (164)

Discovery of TYR inhibitors from de novo molecular generation to dual-track lead optimization: "Competition" between AI and chemists. [PDF]

Sci Adv
Sun Y, Wang J, Chen W, Jiang X, Wang S, Zhi J, Li F, Feng M, Niu X, Ju B, Guo J, Bai R.   +11 more
europepmc   +1 more source

Design, Synthesis, and Evaluation of Novel Thiazole-Based Peptidomimetic Compounds as Potent SARS-CoV-2 Main Protease Covalent Inhibitors. [PDF]

ACS Infect Dis
Yin W, Kong WP, Leung SL, Liang Z, Chen YW, Wong KY.   +5 more
europepmc   +1 more source

Novel bioactive compounds from marine-derived endosymbiotic Penicillium fungi reported during 2020-2025. [PDF]

Nat Prod Bioprospect
Omran SA, Elnaggar MS, Youssef FS, El-Moghazy SA.   +3 more
europepmc   +1 more source

Systematic identification of bacterial neuraminidase inhibitors from <i>Psoralea corylifolia</i> using ultrafiltration-UPLC-Q-Orbitrap-MS and molecular dynamics. [PDF]

J Enzyme Inhib Med Chem
Kim YJ, Jang S, Hwang YH.
europepmc   +1 more source

Structure-Guided Discovery of Novel Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitors. [PDF]

ACS Med Chem Lett
Huang C, Liang M, Zhang P, Liu G, Liao C.   +4 more
europepmc   +1 more source

Hydrazone-schiff base derivatives of 4-(tert-butyl)benzoic acid as potent enzyme inhibitors: In vitro α-amylase, α-glucosidase, tyrosinase inhibition and computational studies. [PDF]

PLoS One
Zghab I, Ahmad S, Ahmad I, Alam A, Mulk S, Aziz Z, Kamal M, Zouidi F, Alharbi AS, Elhenawy AA, Khan M.   +10 more
europepmc   +1 more source

Inhibition of Diabetes-Related Enzymes by Plant Secondary Metabolites: A Promising Therapeutic Strategy. [PDF]

Life (Basel)
Șeremet OC, Andrei C, Pușcașu C, Zanfirescu A, Nițulescu G, Gîrd CE, Olaru OT.   +6 more
europepmc   +1 more source

Phytochemical composition, antioxidant potential, and enzyme inhibitory properties of Onosma thracica extracts: A comparative study of extraction methods. [PDF]

PLoS One
Alshammari M, Sarikurkcu C, Bardakci F, Alreshidi M, Adnan M, Badraoui R, Tepe B.   +6 more
europepmc   +1 more source

Effectiveness of Natural Deep Eutectic Solvents (NADES) in Extracting Bioactive Compounds from <i>Salvia sclarea</i>: HPLC-DAD Analysis, Antioxidant and Enzymes Inhibition Potential Evaluation. [PDF]

ACS Omega
Quradha MM, Duru ME, Kucukaydin S, Qahtan AMF, Khan R, Al Hashedi SA.   +5 more
europepmc   +1 more source

Natural α-Amylase Inhibitors from Medicinal Herbs: In Vitro Evaluation of Extracts Prepared with Food-Compatible Solvents. [PDF]

Foods
Mladenović M, Milutinović M, Đukić N, Rajilić-Stojanović M.   +3 more
europepmc   +1 more source