Results 111 to 120 of about 2,365,869 (296)
Inhibitory effects of the selected title compounds against DNA gyrase.
, 2013 Inhibitory effects of the selected title compounds against DNA gyrase.
Yong Yin (51909) +5 more
core +1 more source
Results in ChemistryThirteen novel 1,2,3-triazole linked nucleobases (5a-m) were designed and efficiently synthesized as potential human enzyme inhibitors. The target compounds were synthesized by using Copper (I)-catalysed Huisgen-Sharpless-Meldal 1,3-dipolar cycloaddition
Aditya Aggarwal +4 more
doaj +1 more source
Mosquito odorant receptor sensitive to natural spatial repellents and inhibitory compounds. [PDF]
Insect Biochem Mol Biol, 2022 Xu P, Choo YM, An S, Leal GM, Leal WS.
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Structures of Compounds Showing Inhibitory Activity against BACE-1.
, 2012 Structures of Compounds Showing Inhibitory Activity against BACE-1.
Li-Hua Zhou (160227) +3 more
core +1 more source
Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B. [PDF]
Antimicrob Agents Chemother, 2021 Pakosz Z +4 more
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2011 Polyphenolic compounds have shown to inhibit toxic effects induced by snake venom proteins. In this work, we demonstrate that gallic acid, ferulic acid, caffeic acid, propylgallate and epigallocatechingallate inhibit the enzymatic activity of a phosphol ...
Quintana Castillo, Juan carlos
core
Minimum Inhibitory Concentration (MIC) of rhodanine compounds Gram-negative pathogens.
, 2016 Minimum Inhibitory Concentration (MIC) of rhodanine compounds Gram-negative pathogens.
Charles R. Ashby Jr (369799) +4 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source