Results 101 to 110 of about 521,946 (359)

Learning of Precise Spike Times with Membrane Potential Dependent Synaptic Plasticity [PDF]

open access: yesarXiv, 2014
Precise spatio-temporal patterns of neuronal action potentials underly e.g. sensory representations and control of muscle activities. However, it is not known how the synaptic efficacies in the neuronal networks of the brain adapt such that they can reliably generate spikes at specific points in time.
arxiv  

Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner. [PDF]

open access: yes, 2017
Medial ganglionic eminence (MGE) transplantation rescues disease phenotypes in various preclinical models with interneuron deficiency or dysfunction, including epilepsy.
Baraban, Scott C, Hsieh, Jui-Yi
core   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

open access: yesAdvanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu   +12 more
wiley   +1 more source

Loss of tumor necrosis factor (TNF)‐receptor 1 and TNF‐receptor 2 partially replicate effects of TNF deficiency on dendritic spines of granule cells in mouse dentate gyrus

open access: yesJournal of Comparative Neurology, Volume 531, Issue 2, Page 281-293, February 2023., 2023
Hippocampal granule cells of adult mice lacking canonical TNF‐Rs were filled with Alexa568 and immunolabeled for Synaptopodin. Morphometric analysis of their spines revealed that TNF‐R mutants partially replicate changes previously reported for TNF‐deficient mice.
Dinko Smilovic   +5 more
wiley   +1 more source

Amyloid-β induces synaptic dysfunction through G protein-gated inwardly rectifying potassium channels in the fimbria-CA3 hippocampal synapse

open access: yesFrontiers in Cellular Neuroscience, 2013
Last evidences suggest that, in Alzheimer's disease (AD) early stage, Amyloid-β (Aβ) peptide induces an imbalance between excitatory and inhibitory neurotransmission systems resulting in the functional impairment of neural networks.
Mauricio O. Nava-Mesa   +4 more
doaj   +1 more source

Novel Solution‐Processed Fe2O3/WS2 Hybrid Nanocomposite Dynamic Memristor for Advanced Power Efficiency in Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
Solution‐processed approach for integration of Fe2O3/WS2 nano‐hybrid composite memristor devices. Remarkable switching characteristics and excellent durability for up to 105 cycles. The device shows ultra‐low energy consumption of 0.072 pJ and excellent environmental stability.
Faisal Ghafoor   +11 more
wiley   +1 more source

Cortical synapses of the world's smallest mammal: An FIB/SEM study in the Etruscan shrew

open access: yesJournal of Comparative Neurology, Volume 531, Issue 3, Page 390-414, February 2023., 2023
The present work provides a quantitative dataset of synapses from the Etruscan shrew (the smallest known terrestrial mammal). We have identified common and differing principles of synaptic organization compared to other mammalian species. Abstract The main aim of the present study was to determine if synapses from the exceptionally small brain of the ...
Lidia Alonso‐Nanclares   +8 more
wiley   +1 more source

Associative properties of structural plasticity based on firing rate homeostasis in recurrent neuronal networks

open access: yes, 2018
Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity.
Gallinaro, Júlia V, Rotter, Stefan
core   +2 more sources

Development of GABAergic and glycinergic transmission in the neonatal rat dorsal horn [PDF]

open access: yes, 2004
Cutaneous spinal sensory transmission appears to lack inhibitory control in the newborn spinal cord, but the properties of GABAergic and glycinergic synapses in the neonatal dorsal horn have not been characterized.
Baccei, ML, Fitzgerald, M
core   +1 more source

Intrinsic Conductances Actively Shape Excitatory and Inhibitory Postsynaptic Responses in Olfactory Bulb External Tufted Cells

open access: yesJournal of Neuroscience, 2008
The initial synapse in the olfactory system is from olfactory nerve (ON) terminals to postsynaptic targets in olfactory bulb glomeruli. Recent studies have disclosed multiple presynaptic factors that regulate this important linkage, but less is known ...
Shaolin Liu, M. T. Shipley
semanticscholar   +1 more source

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