Results 31 to 40 of about 108,206 (318)

Brain injury impairs working memory and prefrontal circuit function

Frontiers in Neurology, 2015
More than 2.5 million Americans suffer a traumatic brain injury (TBI) each year. Even mild to moderate traumatic brain injury causes long-lasting neurological effects.
Colin James Smith, Colin James Smith, Guoxiang eXiong, Jaclynn eElkind, Brendan James Putnam, Akiva eCohen   +5 more
doaj   +1 more source

Modulation of the GABAergic pathway for the treatment of fragile X syndrome. [PDF]

, 2014
Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most common single-gene cause of autism. It is caused by mutations on the fragile X mental retardation gene (FMR1) and lack of fragile X mental retardation ...
Hagerman, Randi J, Hare, Emma B, Lozano, Reymundo   +2 more
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Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
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Interplay between low threshold voltage-gated K+ channels and synaptic inhibition in neurons of the chicken nucleus laminaris along its frequency axis

Frontiers in Neural Circuits, 2014
Central auditory neurons that localize sound in horizontal space have specialized intrinsic and synaptic cellular mechanisms to tightly control the threshold and timing for action potential generation.
William eHamlet, William eHamlet, Yu-Wei eLiu, Zhengquang eTang, Yong eLu, Yong eLu   +5 more
doaj   +1 more source

Dynamical principles in neuroscience [PDF]

, 2006
Dynamical modeling of neural systems and brain functions has a history of success over the last half century. This includes, for example, the explanation and prediction of some features of neural rhythmic behaviors.
Abarbanel, H. D. I., Abarbanel, H. D. I., Abeles, M., Abeles, M., Adrian, E. D., Allen I. Selverston, Amit, D., Amit, D. J., Andronov, A., Andronov, A., Andronov, A. A., Arbib, M. A., Arnold, V., Ashby, W. R., Baird, B., Bartos, M., Bartos, M., Bi, G., Bliss, T. V., Bondarenko, V., Borda, J. C., Canavier, C., Chay, T., Chklovskii, D. B., Cohen, M. A., Crevier, D., Cymbalyuk, G., de Nó, R. L., deCharms, R., Diwadkar, V. A., Duda, R., Elson, R. C., Fano, R. M., Fatt, P., Freeman, W., Freeman, W., Fuhrmann, G., Gallager, R. G., Gavrilov, N., Gerstner, W., Glass, L., Goroff, D., Grossberg, S., Guckenheimer, J., Hatsopoulos, N., Hebb, R., Henry D. I. Abarbanel, Hodgkin, A. L., Hopfield, J., Ichinohe, N., Ince, D., Izhikevich, E., Jones, S. R., Kandel, E. R., Kaplan, D., Katz, B., Kim, U., Kimpo, R. R., Koch, C., Konishi, M., Kuramoto, Y., Kuznetsov, Y., Landau, L. D., Lapicque, L., Lashley, K., Levi, R., Lindner, B., Lotka, A. J., Malkov, V., Maravall, M., Marder, E., Mikhail I. Rabinovich, Nicholls, J. G., Nowotny, T., Oscarsson, O., Ott, E., O’Reilly, R., Pablo Varona, Panchin, Y., Pikovsky, A., Poincaré, A., Poincaré, H., Prinz, A., Prinz, A. A., Rabinovich, M., Ramirez, J., Reinagel, P., Rosenblatt, F., Rowe, D., Saari, G., Segundo, J. P., Segundo, J. P., Senseman, D. M., Seung, H. S., Shadlen, M. N., Shepherd, G., Simmers A. J., Singer, W., Stein, S. G., Strogatz, S. H., Szekely, G., Szücs, A., Szücs, A., Szücs, A., Tsuda, I., Turrigiano, G. G., Varona, P., Volterra, V., Wang, X.-J., Wilson, H. R., Zhigulin, V. P.   +110 more
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GABAB Receptors Augment TRPC3-Mediated Slow Excitatory Postsynaptic Current to Regulate Cerebellar Purkinje Neuron Response to Type-1 Metabotropic Glutamate Receptor Activation

Cells, 2018
During strong parallel fiber stimulation, glutamate released at parallel fiber-Purkinje cell synapses activates type-1 metabotropic glutamate receptor (mGluR1) to trigger a slow excitatory postsynaptic current (sEPSC) in cerebellar Purkinje neurons.
Jinbin Tian, Michael X. Zhu
doaj   +1 more source

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix, Grothe, Benedikt, Meyer, Elisabeth M. M., Porres, Christian P.   +3 more
core   +1 more source

Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]

, 2001
The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
core   +5 more sources

Essential Functions of the Transcription Factor Npas4 in Neural Circuit Development, Plasticity, and Diseases

Frontiers in Neuroscience, 2020
Signaling from the synapse to nucleus is mediated by the integration and propagation of both membrane potential changes (postsynaptic potentials) and intracellular second messenger cascades.
Jian Fu, Ouyang Guo, Zhihang Zhen, Junli Zhen   +3 more
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The positive allosteric modulator of NMDA receptors, GNE‐9278, blocks the ethanol‐induced decrease of excitability in developing retrosplenial cortex neurons from mice

Neuropsychopharmacology Reports, 2023
Binge‐like exposure to ethanol during the brain growth spurt triggers apoptotic neurodegeneration in multiple brain regions, including the retrosplenial cortex, a brain region that is part of the hippocampal‐diencephalic‐cingulate memory network. This is
Clark W. Bird, Carlos F. Valenzuela
doaj   +1 more source