Results 31 to 40 of about 521,946 (359)
Modeling Calcium Dynamics and Inhibition Based Synaptic Plasticity in Dendritic Spines
Mathematical Modelling and Analysis, 2014 Inhibitory synapses through GABAergic channels not only change spine's calcium dynamics but also modulate postsynaptic current mediated through glutamate receptors.
Muhammad Dur-e-Ahmad
doaj +1 more source
Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]
, 1977 The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner +19 more
core +1 more source
Frontiers in Neural Circuits, 2014 Glycinergic inhibition plays a central role in the auditory brainstem circuitries involved in sound localization and in the encoding of temporal action potential firing patterns.
Lina eYassin +6 more
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Phenomenological incorporation of nonlinear dendritic integration using integrate-and-fire neuronal frameworks. [PDF]
PLoS ONE, 2013 It has been discovered recently in experiments that the dendritic integration of excitatory glutamatergic inputs and inhibitory GABAergic inputs in hippocampus CA1 pyramidal neurons obeys a simple arithmetic rule as V(S)(Exp) ≈ V(E)(Exp) + V(I)(Exp) + kV(
Douglas Zhou +3 more
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Frontiers in Molecular Neuroscience, 2022 GABAA receptors are ligand-gated ion channels, which are predominantly permeable for chloride. The neuronal K-Cl cotransporter KCC2 lowers the intraneuronal chloride concentration and thus plays an important role for GABA signaling. KCC2 loss-of-function
Tanja Herrmann +6 more
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Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
, 1979 Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin +2 more
core +1 more source
Imbalance of Excitation and Inhibition at Threshold Level In the Auditory Cortex
Frontiers in Neural Circuits, 2015 The interplay of cortical excitation and inhibition is a fundamental feature of cortical information processing. Excitation and inhibition in single cortical neurons are balanced in their response to optimal sensory stimulation due to thalamocortical ...
Yan eZhao +6 more
doaj +1 more source
Synaptic Integration of Spatiotemporal Features with a Dynamic Neuromorphic Processor [PDF]
2020 International Joint Conference on Neural Networks (IJCNN),
2020, pp. 1-7, 2020 Spiking neurons can perform spatiotemporal feature detection by nonlinear synaptic and dendritic integration of presynaptic spike patterns. Multicompartment models of non-linear dendrites and related neuromorphic circuit designs enable faithful imitation of such dynamic integration processes, but these approaches are also associated with a relatively ...
arxiv +1 more source
Functional maps of neocortical local circuitry
Frontiers in Neuroscience, 2007 This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
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Regulation of Irregular Neuronal Firing by Autaptic Transmission [PDF]
, 2016 The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons participates in the ...
Chen, Mingming +9 more
core +3 more sources