Results 41 to 50 of about 108,206 (318)
Ecotoxicology and Environmental Safety, 2022 Melamine (MEL) and cyanuric acid (CA) alone have relatively low toxicity, but together they may cause serious damage to multiple organs, including the central nervous system, however, the underlying mechanism is unknown. This study aimed to determine and
Wei Sun +5 more
doaj +1 more source
Computational and Structural Biotechnology JournalThe relationship between oxidative stress and glycine receptors is complex, involving multiple mechanisms through which reactive oxygen species can modify glycine receptor function. Understanding these interactions is essential for developing therapeutic
Sanung Eom +9 more
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Journal of Biomedical Science, 2017 Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits ...
Hui Ye, Stephanie Kaszuba
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Alterations in brain connectivity due to plasticity and synaptic delay
, 2017 Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronisation in a ...
Batista, A. M. +8 more
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Development of GABAergic and glycinergic transmission in the neonatal rat dorsal horn [PDF]
, 2004 Cutaneous spinal sensory transmission appears to lack inhibitory control in the newborn spinal cord, but the properties of GABAergic and glycinergic synapses in the neonatal dorsal horn have not been characterized.
Baccei, ML, Fitzgerald, M
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Gain modulation of synaptic inputs by network state in auditory cortex in vivo [PDF]
, 2015 The cortical network recurrent circuitry generates spontaneous activity organized into Up (active) and Down (quiescent) states during slow-wave sleep or anesthesia.
Destexhe, Alain +4 more
core +3 more sources
The energy demand of fast neuronal network oscillations: insights from brain slice preparations
Frontiers in Pharmacology, 2012 Fast neuronal network oscillations in the gamma range (30-100 Hz) in the cerebral cortex have been implicated in higher cognitive functions such as sensual perception, working memory, and, perhaps, consciousness. However, little is known about the energy
Oliver eKann
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Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures [PDF]
, 2012 During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Becker, Denise +8 more
core +2 more sources
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Lithium ameliorates autistic-like behaviors induced by neonatal isolation in rats
Frontiers in Behavioral Neuroscience, 2014 Neonatal isolation is a widely accepted model to study the long-term behavioral changes produced by the early life events. However, it remains unknown whether neonatal isolation can induce autistic-like behaviors, and if so, whether pharmacological ...
Xiaoyan eWu +17 more
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