Results 61 to 70 of about 521,946 (359)
Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
Nature Communications, 2020 Myelination of projection neurons by oligodendrocytes is key to optimize action potential conduction over long distances. However, a large fraction of myelin enwraps the axons of parvalbumin-positive fast-spiking interneurons (FSI), exclusively involved ...
N. Benamer +3 more
semanticscholar +1 more source
Lithium ameliorates autistic-like behaviors induced by neonatal isolation in rats
Frontiers in Behavioral Neuroscience, 2014 Neonatal isolation is a widely accepted model to study the long-term behavioral changes produced by the early life events. However, it remains unknown whether neonatal isolation can induce autistic-like behaviors, and if so, whether pharmacological ...
Xiaoyan eWu +17 more
doaj +1 more source
Tuning a binary ferromagnet into a multi-state synapse with spin-orbit torque induced plasticity [PDF]
Advanced Functional Materials, 29 (25), 1808104 (2019), 2018 Inspired by ion-dominated synaptic plasticity in human brain, artificial synapses for neuromorphic computing adopt charge-related quantities as their weights. Despite the existing charge derived synaptic emulations, schemes of controlling electron spins in ferromagnetic devices have also attracted considerable interest due to their advantages of low ...
arxiv +1 more source
Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling +6 more
wiley +1 more source
Mimicking synaptic plasticity with wedged Pt/Co/Pt spin-orbit torque device [PDF]
J. Phys. D: Appl. Phys. 55, 095001 (2022)We fabricated a wedge-shaped Pt/Co/Pt device with perpendicular magnetic anisotropy and manifested that the Co magnetization can be solely switched by spin-orbit torque without any magnetic field. Similar to the synaptic weight, we observed that the state of Co magnetization (presented by the anomalous Hall resistance RH) of the wedged Pt/Co/Pt device ...
arxiv +1 more source
ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib +16 more
wiley +1 more source
Tunable Tactile Synapses Enabled by Erasable Doping in Iongel‐Gated Nanotube Network Transistors
Advanced Functional Materials, EarlyView.Artificial tactile synaptic sensors are realized by an iongel‐gated single‐walled carbon nanotube (SWCNT) transistor with reversible doping characteristics. The device senses and memorizes tactile stimuli and exhibits gate bias‐dependent excitatory or inhibitory synaptic behavior.
Yan Huang +5 more
wiley +1 more source
Dis-inhibitory neuronal circuits can control the sign of synaptic plasticity [PDF]
arXiv, 2023 How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely functionally motivated models assume distinct neuronal compartments to represent local error signals that determine ...
arxiv
Synaptic Delays for Temporal Feature Detection in Dynamic Neuromorphic Processors [PDF]
Frontiers in Neuroscience; Neuromorphic Engineering (2020), 2019 Spiking neural networks implemented in dynamic neuromorphic processors are well suited for spatiotemporal feature detection and learning, for example in ultra low-power embedded intelligence and deep edge applications. Such pattern recognition networks naturally involve a combination of dynamic delay mechanisms and coincidence detection. Inspired by an
arxiv +1 more source
Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in C. elegans [PDF]
, 2019 Mutations in pre-synaptic voltage gated calcium channels can lead to familial hemiplegic migraine type 1 (FHM1). While mammalian studies indicate that the migraine brain is hyperexcitable due to enhanced excitation or reduced inhibition, the molecular ...
Alkema, Mark J. +9 more
core +1 more source