Depolarizing effect of neocortical chandelier neurons
Chandelier (or axo-axonic) cells are one of the most distinctive types of GABAergic interneurons in the cortex. Although they have traditionally been considered inhibitory neurons, data from rat and human neocortical preparations suggest that chandelier ...
Alan Woodruff+3 more
doaj +1 more source
Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]
The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
core +3 more sources
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong+12 more
wiley +1 more source
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation [PDF]
Gephyrin is a key scaffold protein mediating the anchoring of GABAA receptors at inhibitory synapses. Here, we exploited superresolution techniques combined with proximity-based clustering analysis and model simulations to investigate the single-molecule gephyrin reorganization during plasticity of inhibitory synapses in mouse hippocampal cultured ...
Sebastiano Vascon+12 more
openaire +4 more sources
Development of GABAergic and glycinergic transmission in the neonatal rat dorsal horn [PDF]
Cutaneous spinal sensory transmission appears to lack inhibitory control in the newborn spinal cord, but the properties of GABAergic and glycinergic synapses in the neonatal dorsal horn have not been characterized.
Baccei, ML, Fitzgerald, M
core +1 more source
Hardware Implementation of On‐Chip Hebbian Learning Through Integrated Neuromorphic Architecture
This work presents a neuromorphic hardware platform that integrates presynaptic transistors, threshold switching neurons, and adaptive feedback synapses. The architecture enables on‐chip Hebbian learning through correlation‐based weight updates without external training circuits.
Seonkwon Kim+6 more
wiley +1 more source
Background DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules.
Taesun Yoo+5 more
doaj +1 more source
Distinct forms of synaptic inhibition and neuromodulation regulate calretinin positive neuron excitability in the spinal cord dorsal horn [PDF]
The dorsal horn (DH) of the spinal cord contains a heterogenous population of neurons that process incoming sensory signals before information ascends to the brain.
Boyle, K.A.+6 more
core +1 more source
Organic Ferroelectric Synaptic Transistors for Neural Image Recognition Networks
All organic transistors, where both the dielectric and semiconducting layers are polymeric, are developed as electrical synaptic devices. Two copolymers of PVDF as the dielectric layer with large differences in their saturation polarizability and memory window are chosen.
Evan Restuccia+2 more
wiley +1 more source
During development, hippocampal CA3 network generates recurrent population bursts, so-called Giant Depolarizing Potentials (GDPs). GDPs are characterized by synchronous depolarization and firing of CA3 pyramidal cells followed by afterhyperpolarization ...
Ilgam Khalilov+7 more
doaj +1 more source