Results 81 to 90 of about 276,610 (317)
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source
Vascularized human cortical organoids (vOrganoids) model cortical development in vivo.
Modeling the processes of neuronal progenitor proliferation and differentiation to produce mature cortical neuron subtypes is essential for the study of human brain development and the search for potential cell therapies. We demonstrated a novel paradigm
Yingchao Shi +12 more
doaj +1 more source
Development of GABAergic and glycinergic transmission in the neonatal rat dorsal horn [PDF]
Cutaneous spinal sensory transmission appears to lack inhibitory control in the newborn spinal cord, but the properties of GABAergic and glycinergic synapses in the neonatal dorsal horn have not been characterized.
Baccei, ML, Fitzgerald, M
core +1 more source
Zwitterionic Fluoropolymer‐Engineered Synaptic Clefts Enhance Ion Dynamics in Neuromorphic OECTs
Polyzwitterionic DPVDF (DPVDF‐SZ) ion gels enhance neuromorphic OECT performance due to their reduced crystallinity compared to conventional fluoropolymer (e.g., PVDF‐HFP). These ion gels enable high transconductance, stable ion diffusion, and synaptic plasticity, including long‐term memory. Reservoir computing validation highlights their potential for
Ji Seon Kim +7 more
wiley +1 more source
Approaches and Limitations in the Investigation of Synaptic Transmission and Plasticity
The numbers and strengths of synapses in the brain change throughout development, and even into adulthood, as synaptic inputs are added, eliminated, and refined in response to ongoing neural activity.
Stephen D. Glasgow +4 more
doaj +1 more source
Motor Learning Mechanism on the Neuron Scale
Based on existing data, we wish to put forward a biological model of motor system on the neuron scale. Then we indicate its implications in statistics and learning.
Liu, Peilei, Wang, Ting
core +1 more source
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu +17 more
wiley +1 more source
Last evidences suggest that, in Alzheimer's disease (AD) early stage, Amyloid-β (Aβ) peptide induces an imbalance between excitatory and inhibitory neurotransmission systems resulting in the functional impairment of neural networks.
Mauricio O. Nava-Mesa +4 more
doaj +1 more source
Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice [PDF]
Acid-sensing ion channels (ASIC) open in response to extracellular acidosis. ASIC1a, a particular subtype of these channels, has been described to have a postsynaptic distribution in the brain, being involved not only in ischemia and epilepsy, but also ...
Colettis, Natalia Claudia +8 more
core +1 more source
The initial synapse in the olfactory system is from olfactory nerve (ON) terminals to postsynaptic targets in olfactory bulb glomeruli. Recent studies have disclosed multiple presynaptic factors that regulate this important linkage, but less is known ...
Shaolin Liu, M. T. Shipley
semanticscholar +1 more source

