Results 191 to 200 of about 10,168 (211)
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iNKT cells need UTX-tra demethylation
Nature Immunology, 2017The epigenetic regulation of gene expression by the histone demethylase UTX is central to the development of invariant natural killer cells.
S Harsha, Krovi, Laurent, Gapin
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Ligation of iNKT TCRs as a novel approach to activate iNKT cells for cancer immunotherapy
The Journal of Immunology, 2017Abstract Invariant natural killer T (iNKT) cells are innate-like T cells with an invariant TCRa chain and are restricted by CD1d. The activation of iNKT cells has demonstrated potent anti-tumor activity. Current anti-tumor clinical trials using the iNKT cell ligand, a-galactosylceramide (a-GalCer) have had limited success.
Weiming Yuan +2 more
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iNKT cells for allogeneic cell therapy
Cell and Gene Therapy Insights, 2023Eleni Chantzoura, Paul Ibbett
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Thymic iNKT cell differentiation at single-cell resolution
Cellular & Molecular Immunology, 2021Ke, Wang +3 more
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Challenges of iNKT cell-based antitumor immunotherapies
Cellular & Molecular Immunology, 2020Huimin Zhang, Li Bai
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Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting
Cancer Cell, 2018Antonia Rotolo +2 more
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Cognate interaction with iNKT cells expands IL-10–producing B regulatory cells
Proceedings of the National Academy of Sciences of the United States of America, 2015Emilie E Vomhof-Dekrey +2 more
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How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets
Frontiers in Immunology, 2018Haiguang Wang +2 more
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