Results 251 to 260 of about 738,827 (285)

Natural killer cells, macrophages and dendritic cells as innate immune therapies for blood cancers. [PDF]

Ann Hematol
Oriquat G, Abdulsahib WK, Ismael SH, Roopashree R, Patro PS, Nellore J, Mukherjee G, Chauhan AS, Musayeva S.   +8 more
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Programme of self-reactive innate-like T cell-mediated cancer immunity

Nature, 2022
Cellular transformation induces phenotypically diverse populations of tumour-infiltrating T cells1-5, and immune checkpoint blockade therapies preferentially target T cells that recognize cancer cell neoantigens6,7. Yet, how other classes of tumour-infiltrating T cells contribute to cancer immunosurveillance remains elusive.
Chun Chou, Xian Zhang, Chirag Krishna, Briana G. Nixon, Saida Dadi, Kristelle J. Capistrano, Emily R. Kansler, Miranda Steele, Jian Han, Amy Shyu, Jing Zhang, Efstathios G. Stamatiades, Ming Liu, Shun Li, Mytrang H. Do, Chaucie Edwards, Davina S. Kang, Chin-Tung Chen, Iris H. Wei, Emmanouil P. Pappou, Martin R. Weiser, J. Garcia-Aguilar, J. Joshua Smith, Christina S. Leslie, Ming O. Li   +24 more
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Sympathetic regulation of skin microbiota-induced innate-like T cells

The Journal of Immunology, 2023
Abstract Recent discoveries in microbiota-mediated neuroimmune crosstalk highlight how co-evolved systems collaboratively facilitate host fitness. However, in the skin – the largest and outermost protective barrier – little is known about the role of microbiota in neuro-immune regulation.
Indira N Rao, Michel Enamorado, Dean Merrill, Verena Link, Inta Gribonika, Nicolas Bouladoux, Yasmine Belkaid   +6 more
openaire   +1 more source

Invariant natural killer T cells: innate‐like T cells with potent immunomodulatory activities

Tissue Antigens, 2009
AbstractInvariant natural killer T (iNKT) cells are a subset of T lymphocytes that react with glycolipid antigens presented by the major histocompatibility complex class I‐related glycoprotein CD1d. Although iNKT cells express an antigen‐specific receptor of the adaptive immune system, they behave more like cells of the innate immune system. A hallmark
L, Wu, C L, Gabriel, V V, Parekh, L, Van Kaer   +3 more
openaire   +2 more sources

Metabolic control of innate-like T cells

Nature Reviews Immunology
Thomas Riffelmacher, Mitchell Kronenberg
exaly   +2 more sources

Regulation of innate-like activities of neonatal CD8+ T cells

Nature Reviews Immunology
exaly   +3 more sources

Innate‐like T‐cells correlate with functional changes post‐myocardial infarction

The FASEB Journal, 2022
Cardiovascular disease (CVD) is the leading cause of death in the United States. Ischemic heart failure is caused by adverse remodeling of the infarct scar after a myocardial infarction (MI). CD8+ T‐cells facilitate in the remodeling process and influence scar formation highlighting the importance of these cell types post‐MI ...
Alexa Corker, Philip Broughton, Miguel Troncoso, Kristine Y. Deleon‐Pennell   +3 more
openaire   +1 more source

Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells

2022
AbstractMost human killer cell immunoglobulin-like receptors (KIR) are expressed by Natural Killer (NK) cells and recognize HLA class I molecules as ligands. Uniquely, KIR3DL3 is a conserved but polymorphic inhibitory KIR recognizing a B7 family ligand, HHLA2, and is implicated for immune checkpoint targeting.
William H. Palmer, Laura Ann Leaton, Ana Campos Codo, Patrick S. Hume, Bergren Crute, Matthew Stone, Adrie van Bokhoven, Richard P. Tobin, Martin D. McCarter, William J. Janssen, James Roest, Shiying Zhu, Jan Petersen, Julian P. Vivian, Jamie Rossjohn, John Trowsdale, Andrew Getahun, John Cambier, Liyen Loh, Paul J. Norman   +19 more
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