Results 191 to 200 of about 985,501 (301)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Editorial: Immunesenescence in innate immune cells and disease development. [PDF]

Front Immunol
Mohamed RH.
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

ATG7 in innate immune cells is required for host defense against nontuberculous mycobacterial pulmonary infections. [PDF]

Nat Commun
Jeon SM, Lee YJ, Lee SH, Kim SI, Lee B, Roh T, Kim YJ, Kim HJ, Kim IS, Whang J, Kim SY, Jhun BW, Chung C, Kang DH, Yeo MK, Kim JM, Jang J, Min JJ, Komatsu M, Kim JK, Park WY, Jo EK.   +21 more
europepmc   +1 more source

Mechanosensation to inflammation: Roles for YAP/TAZ in innate immune cells. [PDF]

Sci Signal, 2023
Meli VS, Veerasubramanian PK, Downing TL, Wang W, Liu WF.   +4 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Developmental immune network of airway lymphocytes and innate immune cells in patients with stable COPD. [PDF]

Front Immunol
Liu L, Zhou M, Sun S, Chen L, Li D, Lv J, Cheng R, Zhang J, Wu J, Xiong X.   +9 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Innate immune cells in vascular lesions: mechanism and significance of diversified immune regulation. [PDF]

Ann Med
Wu J, Qian Y, Yang K, Zhang S, Zeng E, Luo D.   +5 more
europepmc   +1 more source

Innate immunity 2 (innate cells) (SY1-2) [PDF]

International Immunology, 2010
openaire   +1 more source