Results 11 to 20 of about 3,110,551 (267)

The Role of Cell Metabolism in Innate Immune Memory [PDF]

open access: yesJournal of Innate Immunity, 2020
Immunological memory is classically attributed to adaptive immune responses, but recent studies have shown that challenged innate immune cells can display long-term functional changes that increase nonspecific responsiveness to subsequent infections ...
Anaisa Valido Ferreira   +2 more
doaj   +6 more sources

Modelling Microglial Innate Immune Memory In Vitro: Understanding the Role of Aerobic Glycolysis in Innate Immune Memory. [PDF]

open access: yesInt J Mol Sci, 2023
Microglia, the resident macrophages of the central nervous system, play important roles in maintaining brain homeostasis and facilitating the brain’s innate immune responses. Following immune challenges microglia also retain immune memories, which can alter responses to secondary inflammatory challenges.
Towriss M, MacVicar B, Ciernia AV.
europepmc   +4 more sources

Innate Immune Memory and the Host Response to Infection. [PDF]

open access: yesJ Immunol, 2022
Unlike the adaptive immune system, the innate immune system has classically been characterized as being devoid of memory functions. However, recent research shows that innate myeloid and lymphoid cells have the ability to retain memory of prior pathogen ...
Sherwood ER   +8 more
europepmc   +5 more sources

Immune memory characteristics of innate lymphoid cells [PDF]

open access: yesCurrent Opinion in Infectious Diseases, 2019
Contains fulltext : 206777.pdf (Publisher’s version ) (Open Access)PURPOSE OF REVIEW: Immune memory is essential for host defense against invaders and it is also used as a basis for vaccine development.
Katarzyna Placek   +8 more
core   +6 more sources

Stroma: the forgotten cells of innate immune memory [PDF]

open access: yesClinical and Experimental Immunology, 2018
SummaryAll organisms are exposed constantly to a variety of infectious and injuriousstimuli. These induce inflammatory responses tailored to the threat posed.While the innate immune system is the front line of response to eachstimulant, it has been ...
Crowley, Thomas   +8 more
core   +5 more sources

Specific memory within innate immune systems

open access: yesTrends in Immunology, 2005
Research into immune defense has been considerably enriched by the increasing focus on innate immunity. This type of immunity is still considered to lack specific memory, largely because there is no evidence of mechanisms that could provide such memory ...
Kurtz, J., Kurtz, Joachim
core   +4 more sources

Innate Immune Memory in Macrophages. [PDF]

open access: yesNewborn (Clarksville), 2023
Macrophages have been recognized as the primary mediators of innate immunity starting from embryonic/fetal development. Macrophage-mediated defenses may not be as antigen-specific as adaptive immunity, but increasing information suggests that these responses do strengthen with repeated immunological triggers. The concept of innate memory in macrophages
Maheshwari A.
europepmc   +3 more sources

Innate immune memory in inflammatory arthritis. [PDF]

open access: yesNat Rev Rheumatol, 2023
The concept of immunological memory was demonstrated in antiquity when protection against re-exposure to pathogens was observed during the plague of Athens. Immunological memory has been linked with the adaptive features of T and B cells; however, in the past decade, evidence has demonstrated that innate immune cells can exhibit memory, a phenomenon ...
Jeljeli MM, Adamopoulos IE.
europepmc   +3 more sources

Innate Immune Memory Responses in Organ Transplantation. [PDF]

open access: yesArterioscler Thromb Vasc Biol
Innate immunity is a critical contributor to graft rejection and cardiovascular complications after organ transplantation, with increasing evidence indicating that innate immune memory significantly influences ...
de Jong LC, Rother N, Duivenvoorden R.
europepmc   +2 more sources

Innate immune memory, trained immunity and nomenclature clarification [PDF]

open access: yesNature Immunology, 2023
Contains fulltext : 295907.pdf (Publisher’s version ) (Open Access)
George Hajishengallis   +2 more
openaire   +3 more sources

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