Interactions between Innate Immune Memory and the Central Nervous System
NeuroimmunomodulationBackground: Traditionally, immunology has assumed the dogma that immunological memory is exclusive to cells of the adaptive immune system. However, over the past decade, evidence has challenged this paradigm by demonstrating that innate immune
Rafaela Rodrigues Valerio +3 more
doaj +2 more sources
Cross-Generational Impact of Innate Immune Memory Following Pregnancy Complications [PDF]
Cells, 2022 Pregnancy complications can have long-term negative effects on the health of the affected mothers and their children. In this review, we highlight the underlying inflammatory etiologies of common pregnancy complications and discuss how aberrant ...
Nakeisha A. Lodge-Tulloch +5 more
doaj +2 more sources
Innate Immune Memory in Invertebrate Metazoans: A Critical Appraisal
Frontiers in Immunology, 2018 The ability of developing immunological memory, a characteristic feature of adaptive immunity, is clearly present also in innate immune responses. In fact, it is well known that plants and invertebrate metazoans, which only have an innate immune system ...
Daniela Melillo +4 more
doaj +3 more sources
Modelling Microglial Innate Immune Memory In Vitro: Understanding the Role of Aerobic Glycolysis in Innate Immune Memory [PDF]
International Journal of Molecular Sciences, 2023 Annie Vogel Ciernia, Brian Macvicar
exaly +2 more sources
Advances in innate immune memory of macrophages
Exploration of Immunology, 2022 Immunity is usually classified into two categories: innate immunity and adaptive immunity, distinguished by the process and characteristics of the immunological impact. It was widely assumed that only adaptive immunity possessed memory features; however,
Safir Ullah Khan, Munir Ullah Khan
doaj +1 more source
In Vivo Zymosan Treatment Induces IL15-Secreting Macrophages and KLRG1-Expressing NK Cells in Mice
Molecules, 2023 Beta-glucan (β-glucan) is a natural polysaccharide produced by fungi, bacteria, and plants. Although it has been reported that β-glucan enhances innate immune memory responses, it is unclear whether different types of β-glucans display similar immune ...
Hyun Jung Park +7 more
doaj +1 more source
Metabolic adaptations driving innate immune memory: mechanisms and therapeutic implications [PDF]
Journal of Leukocyte BiologyBenjamin Klein +2 more
exaly +2 more sources
DAMPs and Innate Immune Training
Frontiers in Immunology, 2021 The ability to remember a previous encounter with pathogens was long thought to be a key feature of the adaptive immune system enabling the host to mount a faster, more specific and more effective immune response upon the reencounter, reducing the ...
Elisa Jentho +3 more
doaj +1 more source
hUCMSCs Mitigate LPS-Induced Trained Immunity in Ischemic Stroke
Frontiers in Immunology, 2020 Innate immune memory is a part of the innate immune system that facilitates the elimination of pathogens. However, it may exacerbate neuropathology. In this study, we found that innate immune memory is detrimental in stroke, because it promotes the acute
Yi-wei Feng +17 more
doaj +1 more source
Emerging Concepts in Innate Lymphoid Cells, Memory, and Reproduction
Frontiers in Immunology, 2022 Members of the innate immune system, innate lymphoid cells (ILCs), encompass five major populations (Natural Killer (NK) cells, ILC1s, ILC2s, ILC3s, and lymphoid tissue inducer cells) whose functions include defense against pathogens, surveillance of ...
Rodolfo R. Favaro +4 more
doaj +1 more source