Results 21 to 30 of about 161,545 (200)

The Role of Cell Metabolism in Innate Immune Memory

open access: yesJournal of Innate Immunity, 2020
Immunological memory is classically attributed to adaptive immune responses, but recent studies have shown that challenged innate immune cells can display long-term functional changes that increase nonspecific responsiveness to subsequent infections ...
Anaisa Valido Ferreira   +2 more
doaj   +1 more source

Recombinant BCG Expressing the Subunit 1 of Pertussis Toxin Induces Innate Immune Memory and Confers Protection against Non-Related Pathogens

open access: yesVaccines, 2022
BCG has shown the ability to induce protection against unrelated pathogens, which likely depends on an immune mechanism known as innate immune memory or trained immunity.
Alex I. Kanno   +3 more
doaj   +1 more source

Microarray expression analysis of genes involved in innate immune memory in peritoneal macrophages

open access: yesGenomics Data, 2016
Immunological memory has been believed to be a feature of the adaptive immune system for long period, but recent reports suggest that the innate immune system also exhibits memory-like reaction.
Keisuke Yoshida   +5 more
doaj   +1 more source

Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. [PDF]

open access: yesPLoS Pathogens, 2011
While immunological memory has long been considered the province of T- and B-lymphocytes, it has recently been reported that innate cell populations are capable of mediating memory responses. We now show that an innate memory immune response is generated
Geoffrey O Gillard   +7 more
doaj   +1 more source

Personalised Profiling of Innate Immune Memory Induced by Nano-Imaging Particles in Human Monocytes

open access: yesFrontiers in Immunology, 2021
Engineered nanoparticles used for medical purposes must meet stringent safety criteria, which include immunosafety, i.e., the inability to activate possibly detrimental immune/inflammatory effects.
Giacomo Della Camera   +13 more
doaj   +1 more source

Differential induction of innate memory in porcine monocytes by -glucan or bacillus Calmette-Guerin

open access: yesInnate Immunity, 2021
Innate immunomodulation via induction of innate memory is one mechanism to alter the host’s innate immune response to reduce or prevent disease. Microbial products modulate innate responses with immediate and lasting effects.
Kristen A Byrne   +2 more
doaj   +1 more source

Transcriptomics and quantitative proteomics reveal changes after second stimulation of bone marrow-derived macrophages from lupus-prone MRL/lpr mice

open access: yesFrontiers in Immunology, 2022
Innate immune memory can cause the occurrence and exacerbation of autoimmune diseases, and it is as well as being strongly associated with the pathogenesis of systemic lupus erythematosus (SLE), however, the specific mechanism remains to be further ...
Keyue Chen   +7 more
doaj   +1 more source

Induction of Innate Immune Memory by Engineered Nanoparticles: A Hypothesis That May Become True

open access: yesFrontiers in Immunology, 2017
Innate immune memory is the capacity of cells of the innate immune system, such as monocytes and macrophages, to react differently to an inflammatory or infectious challenge if previously exposed to the same or to another agent. Innate immune memory is a
Paola Italiani, Diana Boraschi
doaj   +1 more source

A Shift from Cellular to Humoral Responses Contributes to Innate Immune Memory in the Vector Snail Biomphalaria glabrata.

open access: yesPLoS Pathogens, 2016
Discoveries made over the past ten years have provided evidence that invertebrate antiparasitic responses may be primed in a sustainable manner, leading to the failure of a secondary encounter with the same pathogen.
Silvain Pinaud   +11 more
doaj   +1 more source

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