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, 2022 Research on the innate immunity has accelerated over the last decades. The main reason for this has been the discovery of receptors recognizing danger molecules from pathogens.
Bøgwald, Jarl, Dalmo, Roy Ambli
core +3 more sources
libtissue - implementing innate immunity [PDF]
499-506, Proceedings of the IEEE Congress on Evolutionary
Computation (CEC2006), Vancouver, Canada, 2006, 2010 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems. A number of key general properties observed in the biological innate and adaptive immune systems were hughlighted, and how such properties might be ...
Aickelin, Uwe, Twycross, Jamie
arxiv +6 more sources
Innate immunity, assessed by plasma NO measurements, is not suppressed during the incubation fast in eiders [PDF]
Dev. Comp. Immunol. (19/12/2006) 29 pages, 2007 Immunity is hypothesized to share limited resources with other physiological functions and may mediate life history trade-offs, for example between reproduction and survival. However, vertebrate immune defense is a complex system that consists of three components.
Adamo +62 more
arxiv +3 more sources
Innate immunity and neuroinflammation [PDF]
Mediators of Inflammation, 2013 Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core +9 more sources
Experimenting with Innate Immunity [PDF]
SSRN Electronic Journal, 2006 libtissue is a software system for implementing and testing AIS algorithms on real-world computer security problems. AIS algorithms are implemented as a collection of cells, antigen and signals interacting within a tissue compartment.
Aickelin, Uwe, Twycross, Jamie
core +6 more sources
Innate Immunity and MASLD. [PDF]
BiomoleculesMetabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most common liver disease worldwide in recent years. MASLD commonly presents as simple hepatic steatosis, but ~25% of patients develop liver inflammation, progressive fibrosis, liver cirrhosis and related hepatocellular carcinoma.
Meyer M, Schwärzler J, Jukic A, Tilg H.
europepmc +4 more sources
Current Opinion in Immunology, 2010 Innate immunity is an exciting area of research in rhinology because emerging evidence suggests that abnormal local immune responses, rather than pathogen-specific adaptive immunity, may play a more important role in the pathogenesis of chronic rhinosinusitis (CRS).
Artis, D., Tschopp, J.
+10 more sources
On the control of acute rodent malaria infections by innate immunity [PDF]
, 2010 Does specific immunity, innate immunity or resource (red blood cell) limitation control the first peak of the blood-stage parasite in acute rodent malaria infections? Since mice deficient in specific immunity exhibit similar initial dynamics as wild-type
Antia, Rustom +3 more
core +13 more sources
Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection
Cell Death and Disease, 2023 Excessive inflammation and tissue damage during severe influenza A virus (IAV) infection can lead to the development of fatal pulmonary disease. Pyroptosis is a lytic and pro-inflammatory form of cell death executed by the pore-forming protein gasdermin ...
Sarah Rosli +7 more
doaj +1 more source
Nanobodies dismantle post‐pyroptotic ASC specks and counteract inflammation in vivo
EMBO Molecular Medicine, 2022 Inflammasomes sense intracellular clues of infection, damage, or metabolic imbalances. Activated inflammasome sensors polymerize the adaptor ASC into micron‐sized “specks” to maximize caspase‐1 activation and the maturation of IL‐1 cytokines.
Damien Bertheloot +16 more
doaj +1 more source