Results 201 to 210 of about 290,827 (234)

Attenuated <i>Salmonella</i> as a modulator of the cancer-immunity cycle: from innate activation to adaptive antitumor memory. [PDF]

Front Immunol
Chilibroste S, Chabalgoity JA, Moreno M, Mónaco A.   +3 more
europepmc   +1 more source

Interactions between innate and adaptive lymphocytes [PDF]

Nature Reviews Immunology, 2014
Innate lymphocytes - including natural killer cells and the recently discovered innate lymphoid cells - have crucial roles during infection, tissue injury and inflammation. Innate signals regulate the activation and homeostasis of innate lymphocytes. The contribution of the adaptive immune system to the coordination of innate lymphocyte responses is ...
Georg Gasteiger, Alexander Rudensky
exaly   +3 more sources

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Clonal expansion of innate and adaptive lymphocytes

Nature Reviews Immunology, 2020
One of the hallmarks of the vertebrate adaptive immune system is the prolific expansion of individual cell clones that encounter their cognate antigen. More recently, however, there is growing evidence for the clonal expansion of innate lymphocytes, particularly in the context of pathogen challenge.
Nicholas M. Adams, Joseph C Sun, Simon Grassmann   +2 more
exaly   +3 more sources

Innate Lymphocyte Mechanisms in Skin Diseases

Annual Review of Immunology, 2020
Innate lymphocyte populations are emerging as key effectors in tissue homeostasis, microbial defense, and inflammatory skin disease. The cells are evolutionarily ancient and carry conserved principles of function, which can be achieved through shared or unique specific mechanisms.
Clare S Hardman, Graham Ogg, Koshika Yadava   +2 more
exaly   +3 more sources

Innate and Innate-like Effector Lymphocytes in Health and Disease

The Journal of Immunology, 2022
Abstract Lymphocytes can be functionally partitioned into subsets belonging to the innate or adaptive arms of the immune system. Subsets of innate and innate-like lymphocytes may or may not express Ag-specific receptors of the adaptive immune system, yet they are poised to respond with innate-like speed to pathogenic insults but lack ...
Luc Van Kaer, J Luke Postoak, Wenqiang Song, Lan Wu   +3 more
openaire   +2 more sources

Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE [PDF]

Cellular and Molecular Immunology, 2019
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) in which the immune system damages the protective insulation surrounding the nerve fibers that project from neurons. A hallmark of MS and its animal model, experimental autoimmune encephalomyelitis (EAE), is autoimmunity against proteins of the myelin sheath ...
Luc Van Kaer, Lan Wu, Chuan Wang
exaly   +3 more sources

Innate-like Lymphocytes and Innate Lymphoid Cells in Asthma

Clinical Reviews in Allergy & Immunology, 2019
Asthma is a chronic pulmonary disease, highly associated with immune disorders. The typical symptoms of asthma include airway hyperresponsiveness (AHR), airway remodeling, mucus overproduction, and airflow limitation. The etiology of asthma is multifactorial and affected by genetic and environmental factors. Increasing trends toward dysbiosis, smoking,
Chao Huang, Fengqi Li, Jian Wang, Zhigang Tian   +3 more
openaire   +3 more sources