NK Cells and Innate-Like T Cells After Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis [PDF]
Frontiers in Immunology, 2021 Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, in which autoreactive T and B cells play important roles. Other lymphocytes such as NK cells and innate-like T cells appear to be involved as well.
Josefine Ruder +7 more
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It Takes “Guts” to Cause Joint Inflammation: Role of Innate-Like T Cells [PDF]
Frontiers in Immunology, 2018 Innate-like T cells such as invariant natural killer T (iNKT) cells and mucosal-associated T (MAIT) cells, characterized by a semi-invariant T cell receptor and restriction toward MHC-like molecules (CD1 and MR1 respectively), are a unique unconventional
Céline Mortier +7 more
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Developmental features and unique characteristics of peptide-specific PLZF+ innate-like T cells in mice [PDF]
Nature CommunicationsPeptide-specific PLZF+ innate-like T (PILT) cells are a member of the innate-like T cell family utilizing a diverse set of T cell receptor (TCR) Vβ chains.
Ahmed Hassan +6 more
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Innate-like T cells in children with sickle cell disease. [PDF]
PLoS ONE, 2019 BACKGROUND:The implication of lymphocytes in sickle cell disease pathogenesis is supported by a number of recent reports. These studies provided evidence for the activation of invariant natural killer T (iNKT) cells in adult patients, but did not ...
Slimane Allali +8 more
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Interplay between innate-like T-cells and microRNAs in cancer immunity [PDF]
Discover OncologyInnate-like T cells (ILTCs) have recently emerged as a new target of several cancer immunotherapies. Some unique features, such as rapid MHC-independent recognition of antigens, performing heterogeneous anti-tumor activities, and being less susceptible ...
Mohammad Javad Yousefi +7 more
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Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease [PDF]
Frontiers in Immunology, 2020 The immune system plays a significant role in controlling systemic metabolism. Innate-like T (ILT) cells in particular, such as mucosal-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells and γδ T cell receptor expressing cells ...
Yanyan Li +10 more
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Cytotoxic FCER1G+ innate-like T cells: new potential for tumour immunotherapy [PDF]
Signal Transduction and Targeted Therapy, 2022 Emma Morrish, Jürgen Ruland
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The role of innate lymphocytes in regulating brain and cognitive function
Neurobiology of Disease, 2023 Mounting evidence indicates complex interaction between the immune system and the nervous system, challenging the traditional view about the immune privilege of the brain. Innate lymphoid cells (ILCs) and innate-like T cells are unique families of immune
Youwen Si +3 more
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Frontiers in Immunology, 2023 The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce +3 more
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Small Molecule Targeting Immune Cells: A Novel Approach for Cancer Treatment
Biomedicines, 2023 Conventional and cancer immunotherapies encompass diverse strategies to address various cancer types and stages. However, combining these approaches often encounters limitations such as non-specific targeting, resistance development, and high toxicity ...
Shilpi Singh +6 more
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