Results 51 to 60 of about 191,579 (251)

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]

, 2013
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi, A Fortin, A Kahnert, A Mantovani, AM Becker, Anna Giagu, Antonio Giovanni Anfossi, CY Chen, DM Carragher, DM Lowe, E Corsiero, Elisabetta Antuofermo, F Mattei, Fabrizio Mattei, Filippo Belardelli, G Delogu, G Schiavoni, Giovanna Schiavoni, Giovanni Delogu, Giovanni Fadda, HP Gideon, Ivana Palucci, JF Marquis, JG Egen, JL Flynn, K Turcotte, K Turcotte, KB Urdahl, KK Huynh, L Gabriele, L Guglani, L Ramakrishnan, Laura Abalsamo, Lucia Gabriele, M Behr, M Munder, M Sali, Massimo Sanchez, MC Tsai, ME El Shikh, Michela Sali, MP Berry, NA Giese, Olivier Neyrolles, P Tailor, PJ Maglione, RL Hunter, S Hambleton, S Kunnath-Velayudhan, SA Luther, SS Kashino, Stefano Rocca, SY Foo, T Holtschke, T Ulrichs, TA Day, TD Randall, X Zhou, Y Yoshikai   +58 more
core   +3 more sources

T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma

Frontiers in Immunology
Neuroblastoma (NB) is an immunologically “cold” tumor with poor or no inflamed substrates as most of solid pediatric tumors (SPT). Consistent data indicate that NB tumor microenvironment (TME) is dominated by myeloid cells, with little (but variable) T ...
Enrico Maggi, Nadine Landolina, Enrico Munari, Francesca Romana Mariotti, Nicola Tumino, Paola Vacca, Bruno Azzarone, Lorenzo Moretta   +7 more
doaj   +1 more source

Innate Lymphoid Cells in Mucosal Immunity

Frontiers in Immunology, 2019
Innate lymphoid cells (ILCs) are innate counterparts of T cells that contribute to immune responses by secreting effector cytokines and regulating the functions of other innate and adaptive immune cells.
Santosh K. Panda, Marco Colonna
doaj   +1 more source

Innate lymphoid cells: More than just immune cells

Frontiers in Immunology, 2022
Since their discovery, innate lymphoid cells (ILCs) have been described as the innate counterpart of the T cells. Indeed, ILCs and T cells share many features including their common progenitors, transcriptional regulation, and effector cytokine secretion.
Le Xiong, Le Xiong, Stephen L. Nutt, Stephen L. Nutt, Cyril Seillet, Cyril Seillet   +5 more
doaj   +1 more source

Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]

, 2017
No abstract ...
Habenicht, Andreas J.R., Maffia, Pasquale, Mohanta, Sarajo, Yin, Changjun   +3 more
core   +2 more sources

Innate lymphoid cells in secondary lymphoid organs

Immunological Reviews, 2016
SummaryThe family of innate lymphoid cells (ILCs) has attracted attention in recent years as its members are important regulators of immunity, while they can also cause pathology. In both mouse and man, ILCs were initially discovered in developing lymph nodes as lymphoid tissue inducer (LTi) cells.
Bar-Ephraïm, JE, Mebius, Reina E.
openaire   +3 more sources

Innate Lymphoid Cells in Crohn’s Disease

Frontiers in Immunology, 2020
Innate lymphoid cells (ILCs) are a large family of cells of the immune system that performs various functions in immune defense, inflammation, and tissue remodeling. As a part of the innate immune system, ILCs are a distinct form of lymphocytes different
Ying Wu, Jun Shen
doaj   +1 more source

Emerging targets in human lymphoma: targeting the MYD88 mutation [PDF]

, 2016
B cell neoplasms co-opt the molecular machinery of normal B cells for their survival. Technological advances in cancer genomics has significantly contributed to uncovering the root cause of aggressive lymphomas, revealing a previously unknown link ...
Horikawa, Keisuke, Jeelall, Yogesh S., Wang, James Q.   +2 more
core   +1 more source

TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cells

Frontiers in Immunology
BackgroundIn early infected or severe coronavirus disease 2019 (COVID-19) patients, circulating NK cells are consistently reduced, despite being highly activated or exhausted.
Nadine Landolina, Biancamaria Ricci, Irene Veneziani, Claudia Alicata, Francesca Romana Mariotti, Andrea Pelosi, Linda Quatrini, Eva Piano Mortari, Rita Carsetti, Paola Vacca, Nicola Tumino, Bruno Azzarone, Lorenzo Moretta, Enrico Maggi   +13 more
doaj   +1 more source

Immunoregulatory functions of innate lymphoid cells

Journal for ImmunoTherapy of Cancer, 2018
Innate lymphoid cells (ILCs) are increasingly being recognized for their ability to impact both innate and adaptive immune cells in diverse contexts. ILCs have been observed in all secondary lymphoid tissues, in addition to being tissue-resident innate ...
Sarah Q. Crome, Pamela S. Ohashi
doaj   +1 more source