Results 211 to 220 of about 178,465 (247)

Innate immune memory in mammals

open access: yesSeminars in Immunology, 2016
Innate and adaptive immunity have evolved as sophisticated mechanisms of host defence against invading pathogens. Classically the properties attributed to innate immunity are its rapid pleiotropic response, and to adaptive immunity its specificity and ability to retain a long-term memory of past infections.
Melanie Hamon, Jessica Quintin
exaly   +4 more sources

Modelling Microglial Innate Immune Memory In Vitro: Understanding the Role of Aerobic Glycolysis in Innate Immune Memory

open access: yesInternational Journal of Molecular Sciences, 2023
Microglia, the resident macrophages of the central nervous system, play important roles in maintaining brain homeostasis and facilitating the brain’s innate immune responses. Following immune challenges microglia also retain immune memories, which can alter responses to secondary inflammatory challenges.
Annie Vogel Ciernia, Brian Macvicar
exaly   +3 more sources

Innate immune memory: An evolutionary perspective [PDF]

open access: yesImmunological Reviews, 2018
SummaryOver the last decades, there was increasing evidence for the presence of innate immune memory in living organisms. In this review, we compare the innate immune memory of various organisms with a focus on phylogenetics. We discuss the acquisition and molecular basis of immune memory and we describe the innate immune memory paradigm and its role ...
, Simone Moorlag, Gerold Beckers
exaly   +5 more sources

Cardinal features of immune memory in innate lymphocytes

Nature Immunology, 2023
The ability of vertebrates to 'remember' previous infections had once been attributed exclusively to adaptive immunity. We now appreciate that innate lymphocytes also possess memory properties akin to those of adaptive immune cells. In this Review, we draw parallels from T cell biology to explore the key features of immune memory in innate lymphocytes,
Joseph Sun, Endi Santosa, Sun Joseph C
exaly   +3 more sources

Peculiarities of innate immune memory in crustaceans

Fish and Shellfish Immunology, 2020
Classical characteristic of the innate immune system is the lack of ability to build up immunological memory, contrast to the adaptive immune system that is capable of "remembering" antigens, and rapidly mount a greater magnitude of immune response upon subsequent exposure to the same antigens.
, Chou Min Chong
exaly   +3 more sources

Innate immune memory in inflammatory arthritis

Nature Reviews Rheumatology, 2023
The concept of immunological memory was demonstrated in antiquity when protection against re-exposure to pathogens was observed during the plague of Athens. Immunological memory has been linked with the adaptive features of T and B cells; however, in the past decade, evidence has demonstrated that innate immune cells can exhibit memory, a phenomenon ...
Maxime M. Jeljeli, Iannis E. Adamopoulos
openaire   +2 more sources

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