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Memory in the innate and adaptive immune systems
Microbes and Infection, 2004Specific memory is a hallmark of the vertebrate adaptive immune system. However, recent experiments indicate that specific memory might also exist in the innate immune systems of invertebrates. At present, the underlying mechanisms are unknown; yet such phenomenological evidence is relevant for understanding the principles and evolution of immune ...
Joachim Kurtz
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Innate immune memory in plants
Seminars in Immunology, 2016The plant innate immune system comprises local and systemic immune responses. Systemic plant immunity develops after foliar infection by microbial pathogens, upon root colonization by certain microbes, or in response to physical injury. The systemic plant immune response to localized foliar infection is associated with elevated levels of pattern ...
Eva-Maria Reimer-Michalski, Uwe Conrath
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Controlling innate immune memory
Nature Reviews Immunology, 2015Elisabeth Kugelberg +1 more
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Priming Microglia for Innate Immune Memory in the Brain
Trends in Immunology, 2019Microglia, the resident macrophages of the brain, are highly plastic and well known to be pre-activated or 'primed' by active inflammatory processes, resulting in amplified responses to a second inflammatory insult. Furthermore, the capacity of microglia to develop 'innate immune memory' (IIM), that is, long-lasting molecular reprogramming, has ...
Jonas J Neher, Colm Cunningham
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Immunological memory within the innate immune system [PDF]
EMBO Journal, 2014 Immune memory has traditionally been the domain of the adaptive immune system, present only in antigen-specific T and B cells. The purpose of this review is to summarize the evidence for immunological memory in lower organisms (which are not thought to possess adaptive immunity) and within specific cell subsets of the innate immune system.
Eric Vivier +2 more
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Innate Immune Memory and the Host Response to Infection
The Journal of Immunology, 2022Abstract Unlike the adaptive immune system, the innate immune system has classically been characterized as being devoid of memory functions. However, recent research shows that innate myeloid and lymphoid cells have the ability to retain memory of prior pathogen exposure and become primed to elicit a robust, broad-spectrum response to ...
Edward R Sherwood +8 more
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Innate Neutrophil Memory Dynamics in Disease Pathogenesis
2021Neutrophils, the most abundant leukocytes in circulation and the first responders to infection and inflammation, closely modulate both acute and chronic inflammatory processes. Resting neutrophils constantly patrol vasculature and migrate to tissues when challenges occur.
RuiCi, Lin, Liwu, Li
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Train to Lose: Innate Immune Memory in Metaflammation
Molecular Nutrition & Food Research, 2020AbstractWesternized diets and lifestyle are linked to the development of metabolic syndrome, characterized by obesity, type 2 diabetes, and increased cardiovascular disease risk. Systemic low‐grade inflammation is a common feature of chronic metabolic disorders and is believed to promote disease progression.
Hugo Charles‐Messance +1 more
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The immune memory of innate immune systems
International ImmunologyAbstract Immune memory has long been considered a function specific to adaptive immune systems; however, adaptive immune memory alone has not fully explained the mechanism by which vaccines exert their protective effects against nontarget pathogens.
Yasuhiro Kato, Atsushi Kumanogoh
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2018
Recent years have seen a surge in studies on insect immune memory. Here we provide an overview of the current state of evidence for immune memory mechanisms in insects. This group of animals is very heterogeneous, and understanding of the molecular mechanisms behind immune memory remains fragmentary.
Humberto Lanz-Mendoza +1 more
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Recent years have seen a surge in studies on insect immune memory. Here we provide an overview of the current state of evidence for immune memory mechanisms in insects. This group of animals is very heterogeneous, and understanding of the molecular mechanisms behind immune memory remains fragmentary.
Humberto Lanz-Mendoza +1 more
openaire +1 more source