Results 21 to 30 of about 1,266 (160)

Independent Innexin Radiation Shaped Signaling in Ctenophores [PDF]

Molecular Biology and Evolution, 2023
Joseph Ryan, Keith A Crandall, Mark Q Martindale   +2 more
exaly   +2 more sources

Identification and classification of innexin gene transcripts in the central nervous system of the terrestrial slug Limax valentianus.

PLoS ONE, 2021
Intercellular gap junction channels and single-membrane channels have been reported to regulate electrical synapse and the brain function. Innexin is known as a gap junction-related protein in invertebrates and is involved in the formation of ...
Hisayo Sadamoto, Hironobu Takahashi, Suguru Kobayashi, Hirooki Kondoh, Hiroshi Tokumaru   +4 more
doaj   +1 more source

Contribution of large-pore channels to inflammation induced by microorganisms

Frontiers in Cell and Developmental Biology, 2023
Plasma membrane ionic channels selectively permeate potassium, sodium, calcium, and chloride ions. However, large-pore channels are permeable to ions and small molecules such as ATP and glutamate, among others.
José L. Vega, José L. Vega, José L. Vega, Camila Gutiérrez, Mauro Rojas, Juan Güiza, Juan C. Sáez   +6 more
doaj   +1 more source

A new player in circadian networks: Role of electrical synapses in regulating functions of the circadian clock

Frontiers in Physiology, 2022
Several studies have indicated that coherent circadian rhythms in behaviour can be manifested only when the underlying circadian oscillators function as a well-coupled network.
Aishwarya Ramakrishnan Iyer, Aishwarya Ramakrishnan Iyer, Vasu Sheeba   +2 more
doaj   +1 more source

Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool

eLife, 2022
Gap-junctional signaling mediates myriad cellular interactions in metazoans. Yet, how gap junctions control the positioning of cells in organs is not well understood. Innexins compose gap junctions in invertebrates and affect organ architecture. Here, we
Theadora Tolkin, Ariz Mohammad, Todd A Starich, Ken CQ Nguyen, David H Hall, Tim Schedl, E Jane Albert Hubbard, David Greenstein   +7 more
doaj   +1 more source

Innexin expression and localization in the Drosophila antenna indicate gap junction or hemichannel involvement in antennal chemosensory sensilla. [PDF]

Cell Tissue Res
<jats:title>Abstract</jats:title><jats:p>Odor detection in insects is largely mediated by structures on antennae called sensilla, which feature a strongly conserved architecture and repertoire of olfactory sensory neurons (OSNs) and ...
Prelic S, Keesey IW, Lavista-Llanos S, Hansson BS, Wicher D.   +4 more
europepmc   +2 more sources

Analysis of Hemichannels and Gap Junctions: Application and Extension of the Passive Transmembrane Ion Transport Model

Frontiers in Cellular Neuroscience, 2021
Electrical synaptic transmission is an essential form of interneuronal communication which is mediated by gap junctions that permit ion flow. Three gene families (connexins, innexins, and pannexins) have evolved to form gap junctional channels.
Qiqian Wang, Shenquan Liu
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

British Journal of Pharmacology, Volume 180, Issue S2, Page S145-S222, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jörg Striessnig, Eamonn Kelly, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Alex C. Conner, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, Chandy George, Steve A. N. Goldstein, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Perez‐Reyes, Leigh D. Plant, Lachlan Rash, Dejian Ren, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Joris Vriens, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Wei Fang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +72 more
wiley   +1 more source

Polydnavirus Innexins Disrupt Host Cellular Encapsulation and Larval Maturation

Viruses, 2021
Polydnaviruses are dsDNA viruses associated with endoparasitoid wasps. Delivery of the virus during parasitization of a caterpillar and subsequent virus gene expression is required for production of an amenable environment for parasitoid offspring ...
Peng Zhang, Matthew Turnbull
doaj   +1 more source

Impact of dual‐baculovirus infection on the Sf9 insect cell transcriptome during rAAV production using single‐cell RNA‐seq

Biotechnology and Bioengineering, Volume 120, Issue 9, Page 2588-2600, September 2023., 2023
Single‐cell RNA sequencing was employed for the first time in Sf9 insect cell culture, to study the production of recombinant adeno‐associated virus (rAAV) using a dual baculovirus expression vector system (BEVS). The results highlight significant heterogeneity within the cell population during production.
Nikolaus Virgolini, Marco Silvano, Ryan Hagan, Ricardo Correia, Paula M. Alves, Colin Clarke, António Roldão, Inês A. Isidro   +7 more
wiley   +1 more source