Results 11 to 20 of about 1,143 (172)
AbstractConnexins were first identified in the 1970s as the molecular components of vertebrate gap junctions. Since then a large literature has accumulated on the cell and molecular biology of this multiāgene family culminating recently in the findings that connexin mutations are implicated in a variety of human diseases.
P, Phelan, T A, Starich
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Bracovirus-mediated innexin hemichannel closure in cell disassembly [PDF]
Summary: Cell-cell communication is necessary for cellular immune response. Hemichannel closure disrupts communication between intracellular and extracellular environments during polydnavirus-induced immunosuppression in invertebrates.
Chang-Xu Chen +11 more
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Innexins are a family of membrane proteins involved in the formation of gap junctions in invertebrates. They have been found to participate in several aspects of cell differentiation and in embryonic patterning through the formation of specific intercellular communication channels.
POTENZA N. +4 more
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Functional Interactions between Polydnavirus and Host Cellular Innexins [PDF]
ABSTRACT Polydnaviruses are double-stranded DNA viruses associated with some subfamilies of ichneumonoid parasitoid wasps. Polydnavirus virions are delivered during wasp parasitization of a host, and virus gene expression in the host induces alterations of host physiology.
N K, Marziano +3 more
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Identification and classification of innexin gene transcripts in the central nervous system of the terrestrial slug Limax valentianus. [PDF]
Intercellular gap junction channels and single-membrane channels have been reported to regulate electrical synapse and the brain function. Innexin is known as a gap junction-related protein in invertebrates and is involved in the formation of ...
Hisayo Sadamoto +4 more
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Mosquitoes are vectors of pathogens that cause diseases of medical and veterinary importance. Female mosquitoes transmit these pathogens while taking a blood meal, which most species require to produce eggs.
Travis L. Calkins, Peter M. Piermarini
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AFD thermosensory neurons mediate tactile-dependent locomotion modulation in C. elegans [PDF]
Sensory neurons drive animal behaviors by detecting environmental stimuli and relaying information to downstream circuits. Beyond their primary roles in sensing, these neurons often form additional synaptic connections outside their main sensory modality,
Manuel Rosero, Jihong Bai
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Long-term potentiation in an innexin-based electrical synapse [PDF]
Electrical synapses are formed by two unrelated gap junction protein families, the primordial innexins (invertebrates) or the connexins (vertebrates). Although molecularly different, innexin- and connexin-based electrical synapses are strikingly similar ...
Georg Welzel, Stefan Schuster
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Innexins: members of an evolutionarily conserved family of gap-junction proteins [PDF]
Gap junctions are clusters of intercellular channels that provide cells, in all metazoan organisms, with a means of communicating directly with their neighbours. Surprisingly, two gene families have evolved to fulfil this fundamental, and highly conserved, function.
Phelan, Pauline
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Molecular characterization and embryonic expression of innexins in the leech Hirudo medicinalis
Gap junctions are direct intercellular channels that permit the passage of ions and small signaling molecules. The temporal and spatial regulation of gap junctional communication is, thus, one mechanism by which cell interactions, and hence cell properties and cell fate, may be regulated during development.
Dykes, Iain M, Macagno, Eduardo R
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