Results 41 to 50 of about 1,143 (172)

RNA viruses alter house dust mite physiology and allergen production with no detected consequences for allergenicity

Insect Molecular Biology, Volume 32, Issue 2, Page 173-186, April 2023., 2023
The infection of the European house dust mite with RNA viruses affects the expression of allergen‐related, immunity and stress‐response genes. Major allergen Der p 23 is upregulated (with ELISA titres increasing in culture extracts), whilst serine protease allergens Der p 3, 6 and 9 are downregulated (trypsin and chymotrypsin activities reduced).
José Cristian Vidal‐Quist, Jozefien Declercq, Stijn Vanhee, Bart N Lambrecht, José Gómez‐Rial, Carmen Vidal, Eylem Aydogdu, Stephane Rombauts, Pedro Hernández‐Crespo   +8 more
wiley   +1 more source

Distinct patterns of gene expression during regeneration and asexual reproduction in the annelid Pristina leidyi

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 338, Issue 7, Page 405-420, November 2022., 2022
Summary of the workflow developed in this study. Abstract Regeneration, the ability to replace lost body parts, is a widespread phenomenon in the animal kingdom often connected to asexual reproduction or fission, since the only difference between the two appears to be the stimulus that triggers them.
Irene del Olmo, Aida Verdes, Patricia Álvarez‐Campos   +2 more
wiley   +1 more source

Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities

MedComm, Volume 3, Issue 2, June 2022., 2022
Epithelial–mesenchymal transition contributes to multiple hallmarks of cancer, including metastasis activation, metabolic reprogramming, stemness acquisition, and chronic inflammation, which is regulated by complex signaling network and is highly context dependent.
Zhao Huang, Zhe Zhang, Chengwei Zhou, Lin Liu, Canhua Huang   +4 more
wiley   +1 more source

Evolutionary Diversification of Insect Innexins [PDF]

Journal of Insect Science, 2014
Phylogenetic analysis of insect innexins supported the hypothesis that six major clades of insect innexins arose by gene duplication prior to the origin of the endopterygote insects. Within one of the six clades (the Zpg Clade), two independent gene duplication events were inferred to have occurred in the lineage of Drosophila, after the most recent ...
openaire   +2 more sources

Integration of Migratory Cells into a New Site In Vivo Requires Channel-Independent Functions of Innexins on Microtubules [PDF]

, 2020
During embryonic development and cancer metastasis, migratory cells must establish stable connections with new partners at their destinations. Here, we establish the Drosophila border cells as a model for this multistep process.
Godt, Dorothea, Montell, Denise J, Miao, Guangxia   +2 more
core   +1 more source

Shaking B Mediates Synaptic Coupling between Auditory Sensory Neurons and the Giant Fiber of Drosophila melanogaster.

PLoS ONE, 2016
The Johnston's Organ neurons (JONs) form chemical and electrical synapses onto the giant fiber neuron (GF), as part of the neuronal circuit that mediates the GF escape response in Drosophila melanogaster.
Adeline P Pézier, Sami H Jezzini, Jonathan P Bacon, Jonathan M Blagburn   +3 more
doaj   +1 more source

Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool

eLife, 2022
Gap-junctional signaling mediates myriad cellular interactions in metazoans. Yet, how gap junctions control the positioning of cells in organs is not well understood. Innexins compose gap junctions in invertebrates and affect organ architecture. Here, we
Theadora Tolkin, Ariz Mohammad, Todd A Starich, Ken CQ Nguyen, David H Hall, Tim Schedl, E Jane Albert Hubbard, David Greenstein   +7 more
doaj   +1 more source

Bracovirus Sneaks Into Apoptotic Bodies Transmitting Immunosuppressive Signaling Driven by Integration-Mediated eIF5A Hypusination

Frontiers in Immunology, 2022
A typical characteristics of polydnavirus (PDV) infection is a persistent immunosuppression, governed by the viral integration and expression of virulence genes.
Gui-Fang Zhou, Gui-Fang Zhou, Chang-Xu Chen, Chang-Xu Chen, Qiu-Chen Cai, Qiu-Chen Cai, Xiang Yan, Xiang Yan, Nan-Nan Peng, Nan-Nan Peng, Xing-Cheng Li, Xing-Cheng Li, Ji-Hui Cui, Ji-Hui Cui, Yun-Feng Han, Yun-Feng Han, Qi Zhang, Qi Zhang, Jiang-Hui Meng, Jiang-Hui Meng, Hong-Mei Tang, Hong-Mei Tang, Chen-hui Cai, Chen-hui Cai, Jin Long, Jin Long, Kai-Jun Luo, Kai-Jun Luo   +27 more
doaj   +1 more source

The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition

eLife, 2020
Pannexins are large-pore forming channels responsible for ATP release under a variety of physiological and pathological conditions. Although predicted to share similar membrane topology with other large-pore forming proteins such as connexins, innexins ...
Kevin Michalski, Johanna L Syrjanen, Erik Henze, Julia Kumpf, Hiro Furukawa, Toshimitsu Kawate   +5 more
doaj   +1 more source

Pannexin2 oligomers localize into endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane

Frontiers in Cellular Neuroscience, 2015
Pannexin2 (Panx2) is the largest of three members of the pannexin proteins. Pannexins are topologically related to connexins and innexins, but serve different functional roles than forming gap junctions.
Daniela eBoassa, Phuong eNguyen, Junru eHu, Mark H Ellisman, Gina E. Sosinsky   +4 more
doaj   +1 more source