Results 51 to 60 of about 1,143 (172)
Identification of Innexins Contributing to Giant-Fiber Escape Responses in Marbled Crayfish
, 2020 Gap junctions form intercellular pores that coordinate the flow of electrical signals between adjacent cells in the nervous system. While the physiology of electrical synapses has been investigated in sophisticated detail, the molecular underpinnings of ...
Benson, Abigail Marie
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Are there gap junctions without connexins or pannexins?
BMC Evolutionary Biology, 2019 Background Gap junctions (GJ) are one of the most common forms of intercellular communication. GJs are assembled from proteins that form channels connecting the cytoplasm of adjacent cells.
Georgy A. Slivko-Koltchik +2 more
doaj +1 more source
Innexin expression in electrically coupled motor circuits
Neuroscience Letters, 2019 The many roles of innexins, the molecules that form gap junctions in invertebrates, have been explored in numerous species. Here, we present a summary of innexin expression and function in two small, central pattern generating circuits found in crustaceans: the stomatogastric ganglion and the cardiac ganglion.
Otopalik, Adriane G. +3 more
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Cytoskeletal Regulation by the Gap Junction Forming Proteins Innexins
, 2021 https://rdc.reed.edu/v1/resources/e23e2bb8-08f8-4a61-a960-db8dac8b64f1/thumb/128.jpgIn cellular migratory events such as metastasis and morphogenesis in embryonic development, cells must form new stable cell-cell contacts once they reach their ...
Garcia, Segovia
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Structure Function Analysis of Innexin ShakingB(Lethal) [PDF]
Biophysical Journal, 2012 ShakingB(Lethal) is a gap junction protein that contributes to rectifying synapses of the Drosophila Giant Fiber System. Like other innexins, ShakingB (lethal) spans the membrane four times (M1-M4) with cytoplasmic amino and carboxyl termini. Tryptophan-scanning analysis, recently applied to ShakingB(Lethal) confirmed that the first transmembrane ...
DePriest, Adam D. +2 more
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Ectopic Expression of Select Innexins in Individual Central Neurons Couples Them to Pre-Existing Neuronal or Glial Networks That Express the Same Innexin [PDF]
The Journal of Neuroscience, 2012 Fifteen of the 21 innexin (Inx) genes (Hve-inx) found in the genome of the medicinal leech,Hirudo verbana, are expressed in the CNS (Kandarian et al., 2012). Two are expressed pan-neuronally, while the others are restricted in their expression to small numbers of cells, in some cases reflecting the membership of known networks of electrically coupled ...
Constantine P, Firme +4 more
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Do Innexins function in the extreme cold response of Drosophila melanogaster [PDF]
, 2020 Nociception is an organism’s ability to detect, process and reflexively respond to potentially damaging stimuli. While the process of nociception has clear, protective advantages, inappropriate and prolonged signaling can lead to chronic pain in humans ...
Ward, Madison A.
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Chimeric Innexins Reveal Complexities of Electrical Rectification [PDF]
Biophysical Journal, 2017 The innexins ShakingB Lethal (SBL) and ShakingB Neural+16 (SBN16) form heterotypic gap junctions in the Giant Fiber System of Drosophilia melanogaster. The junctions favor arthodromic transmission of action potentials and exhibit properties of rectification when expressed in vivo.
Jamal B. Williams, Martha Skerrett
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Pannexin1 stabilizes synaptic plasticity and is needed for learning. [PDF]
PLoS ONE, 2012 Pannexin 1 (Panx1) represents a class of vertebrate membrane channels, bearing significant sequence homology with the invertebrate gap junction proteins, the innexins and more distant similarities in the membrane topologies and pharmacological ...
Nora Prochnow +10 more
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Genetic engineering for SIT application: a fruit fly‐focused review
Insect Science, Volume 33, Issue 2, Page 703-723, April 2026.Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova +2 more
wiley +1 more source