Results 101 to 110 of about 70,058 (185)

Activated Inositol Phosphate, Substrate for Synthesis of Prostaglandylinositol Cyclic Phosphate (Cyclic PIP)-The Key for the Effectiveness of Inositol-Feeding. [PDF]

Int J Mol Sci
Gypakis A, Adelt S, Lemoine H, Vogel G, Wasner HK.   +4 more
europepmc   +1 more source

TaRIP2 Positively Regulates Wheat Pollen Wall Formation Through MYB80‐Controlled Lipid Metabolism

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2595-2606, April 2026.
ABSTRACT Male‐sterile genes and mutants are critical for hybrid seed production in monocotyledonous crops. Lipids are essential structural components of male reproductive organs, such as the anther and pollen. Here, we show that the pollen‐preferential gene TaRIP2 is essential for wheat anther development and pollen formation. RT‐qPCR analysis revealed
Ran Han, Aifeng Liu, Guang Qi, Chunhao Fang, XiaoLu Wang, Wenjing Xu, Kai Wang, Jihu Li, Qingqi Fan, Dungong Cheng, Faji Li, Haosheng Li, Jianjun Liu, Genying Li, Cheng Liu   +14 more
wiley   +1 more source

Several plant self‐incompatibility systems may be controlled by atypical receptor–ligand interactions

The Plant Journal, Volume 126, Issue 1, April 2026.
SUMMARY Self‐incompatibility (SI) is the single most important mechanism utilized by flowering plants to avoid self‐fertilization, thus preventing inbreeding and promoting outcrossing. Many plant SI systems are genetically controlled by a multi‐allelic S‐locus, containing two tightly linked genes that encode the female and male S‐determinants.
Zongcheng Lin, Maurice Bosch, Vernonica E. Franklin‐Tong   +2 more
wiley   +1 more source

ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell‐Type Dependent and Tied to Ceramide Homeostasis

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
ORMDL proteins in the endoplasmic reticulum (ER) negatively regulate serine palmitoyltransferase (SPT) activity in response to the rate of de novo sphingolipid synthesis. Disruption of ceramide homeostasis by myriocin or fumonisin B1 (FB1) appears to destabilize the ORMDL‐SPT complex, leading to ORMDL degradation as a feedback mechanism.
Michal Mrkacek, Magda Tumova, Alex Puskasu, Pavol Utekal, Marek Vrbacky, Ladislav Kuchar, Petr Draber, Viktor Bugajev   +7 more
wiley   +1 more source

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual‐Acting Compounds

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
This study explores the development of dual‐acting compounds combining σ1R agonists and histone deacetylase inhibitors (HDACi). Key findings include compound 2d and 3a's high affinity for σ1R and favorable pharmacokinetic profile and an in vivo determined σ1R agonist profile by reversing the effect of the σ1R antagonist BD‐1063.
Antonino N. Fallica, Carla Barbaraci, M. Carmen Ruiz‐Cantero, Arianna Scarlatti, Alessandro Coco, Giorgia Giordano, Alfonsina La Mantia, Orazio Prezzavento, Antonio Di Stefano, Ivana Cacciatore, Giacomo Siano, Antonino Cattaneo, Lorella Pasquinucci, Enrique J. Cobos, Cristina Di Primio, Emanuele Amata, Agostino Marrazzo   +16 more
wiley   +1 more source

Effect of dietary calcium source, exogenous phytase, and formic acid on inositol phosphate degradation, mineral and amino acid digestibility, and microbiota in growing pigs. [PDF]

J Anim Sci
Klein N, Sarpong N, Feuerstein D, Camarinha-Silva A, Rodehutscord M.   +4 more
europepmc   +1 more source

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. [PDF]

Mol Cell, 2018
Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE.   +17 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Inositol Phosphate Metabolism

Reactome - a curated knowledgebase of biological pathways, 2012
openaire   +1 more source