Results 121 to 130 of about 494,776 (288)

Adrenergic stimulation of inositol phosphate accumulation in tracheal epithelium

, 1989
To determine whether inositol phosphates are important second messengers in the regulation of Cl- secretion by airway epithelia, we examined the relationship between inositol phosphate accumulation and Cl- secretion in response to adrenergic agonists ...
M. J. Welsh, T. Bainbridge, R. D. Feldman   +2 more
core   +1 more source

Salidroside Alleviates AlCl3/D‐galactose‐Induced Alzheimer's Disease‐Like Mice Neuronal Damage and Synaptic Dysfunction Through Keap1/Nrf2/GSH Signaling Axis

Phytotherapy Research, EarlyView.
Salidroside alleviates AlCl3/D‐galactose‐induced neuronal injury and synaptic dysfunction in AD‐like mice via regulation of the Keap1/Nrf2/GSH signaling axis. ABSTRACT Alzheimer's disease (AD) is associated with glutathione (GSH) depletion and redox imbalance in the brain, contributing to hippocampal neuronal damage and synaptic dysfunction and ...
Heying Cui, Yihua Han, Yanzhu Lu, Shuhua Zheng, Ruijing Zhang, Xianjing Zhang, Zheng Nan, Xiangdan Li, Songbiao Cui, Dongyuan Xu   +9 more
wiley   +1 more source

Synthesis of novel phosphorothioate and pyrophosphate analysis of inositol phosphates.

, 1992
A novel synthesis of cyclic pyrophosphates was developed. The vicinal bisphosphorothioate, l-phenyl-ethane-l,2-bisphosphorothioate, was synthesised using phosphorus (III) chemistry.
Nicholas Jason. Noble (7697780)
core   +4 more sources

HIV-1 capsid stability enables inositol phosphate-independent infection of target cells and promotes integration into genes. [PDF]

PLoS Pathog, 2023
Sowd GA, Shi J, Fulmer A, Aiken C.
europepmc   +1 more source

Purification and properties of myo-inositol-1-phosphate dehydrogenase from germinating mung bean seeds

, 1984
A novel enzyme, myo-inositol-1-phosphate dehydrogenase, which catalyzes the conversion of myo-inositol 1-phosphate to ribulose 5-phosphate has been purified 84-fold from mung bean seedling employing several common techniques. The molecular weight of this
Biswas, B. B., De, B. P., Ghosh, B.
core   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Structural basis of phosphate export by human XPR1

Nature Communications
Phosphorus in crucial for all living organisms. In vertebrate, cellular phosphate homeostasis is partly controlled by XPR1, a poorly characterized inositol pyrophosphate-dependent phosphate exporter.
Qixian He, Ran Zhang, Sandrine Tury, Valérie Courgnaud, Fenglian Liu, Jean-luc Battini, Baobin Li, Qingfeng Chen   +7 more
doaj   +1 more source

Adsorption of Inositol Phosphate on Hydroxyapatite Powder with High Specific Surface Area. [PDF]

Materials (Basel), 2022
Minamisawa H, Kojima Y, Aizawa M.
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source