Results 111 to 120 of about 761,638 (295)

Untargeted Metabolomics Reveals Seasonal and Tissue‐Specific Metabolic Shifts in Holothuria cinerascens

Chemistry &Biodiversity, EarlyView.
Untargeted metabolic profiling of three body tissues from Holothuria cinerascens in South Africa using 1H‐NMR and UPLC–QTOF–MS revealed distinct tissue‐specific and seasonal metabolic variations, with the body wall and gut/mesentery exhibiting high metabolite diversity.
Cassandra Upton, Gerhard Prinsloo, Paul Steenkamp, Moses Okpeku   +3 more
wiley   +1 more source

Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]

, 2010
Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana, Giusto, Norma Maria, Guido, Mario Eduardo, Ilincheta, Monica Graciela, Salvador, Gabriela Alejandra, Verra, Daniela Mariana   +5 more
core   +1 more source

Arginine Transcriptional Response Does Not Require Inositol Phosphate Synthesis*

Journal of Biological Chemistry, 2012
Background: The involvement of inositol phosphates produced by the yeast inositol-polyphosphate multikinase, Arg82, in transcription is controversial. Results: Catalytically inactive Arg82 restores the regulation of arginine-dependent genes in an ARG82 ...
D. Bosch, A. Saiardi
semanticscholar   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Adipose Inositol Monophosphate Metabolism Is Associated with Fasting Regimen-Elicited Metabolic Benefits

Biomolecules
Intermittent fasting (IF) has emerged as a promising strategy for managing obesity and related metabolic disorders. Although metabolic adaptations in adipose tissue during IF are well documented, the specific reprogramming of white adipose tissue (WAT ...
Chunqing Wang, Bilian Liu, Xin Yang, Xi Chen, Shuo Wang, Xing Zhang, Meilian Liu   +6 more
doaj   +1 more source

Allelic Variants of CRISPR/Cas9 Induced Mutation in an Inositol Trisphosphate 5/6 Kinase Gene Manifest Different Phenotypes in Barley

Plants, 2020
Inositol trisphosphate 5/6 kinases (ITPK) constitute a small group of enzymes participating in the sequential phosphorylation of inositol phosphate to inositol hexakisphosphate (IP6), which is a major storage form of phosphate in cereal grains.
Tomáš Vlčko, Ludmila Ohnoutková
doaj   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

IRBIT a Master Regulator of Cell Physiology [PDF]

, 2017
(excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G, Cook, Kelli, Petreska, Natasa   +2 more
core   +1 more source

Talented family: Inositol phosphates [PDF]

The Biochemist, 2009
So, what's a review on inositol phosphates doing in a nice lipid-themed place like this? (given how watersoluble and un-lipiddy they are). But they are, at least in animal cells, inextricably linked with inositol lipids. The link is the phospholipase C (PI-PLC) reaction, which splits phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] into ...
openaire   +1 more source

Inositol phosphate signaling and gibberellic acid [PDF]

Plant Signaling & Behavior, 2009
To respond to physical signals and endogenous hormones, plants use specific signal transduction pathways. We and others have previously shown that second messenger inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] is used in abscisic acid (ABA) signaling, and that some mutants with altered Ins(1,4,5)P(3) have altered responses to ABA. Specifically, mutants
Christine M, Fleet, Mustafa E, Ercetin, Glenda E, Gillaspy   +2 more
openaire   +2 more sources