The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes. [PDF]
Pytel WA +11 more
europepmc +1 more source
Pinus‐derived membrane vesicles disrupt pathogenic metabolism in fungi
Needle‐derived vesicles from pine trees impair fungal metabolism and growth, offering a sustainable strategy to control pine pitch canker disease. Abstract Much of what we know about the biological impacts of vesicles (MVs) is derived from Arabidopsis thaliana.
S. Kunene +3 more
wiley +1 more source
Phosphorus-specific, liquid chromatography inductively coupled plasma mass spectrometry for analysis of inositol phosphate and inositol pyrophosphate metabolism. [PDF]
Sprigg C +12 more
europepmc +1 more source
Integrated Multi-Omics Analysis of <i>Polygonatum odoratum</i> Polysaccharide in D-Galactose-Treated Mice Reveals Changes in Oxidative Stress Markers and Gut Microbiota. [PDF]
This study evaluated the effects of Polygonatum odoratum polysaccharide (POP) in D‐galactose‐treated mice using hippocampal histology, oxidative stress measurements, and integrated multi‐omics analyses. Results showed improved hippocampal histology and oxidative stress markers, accompanied by changes in gut bacterial composition, serum metabolites, and
Li W, Huang Y, Zhang W, Li S, Li L.
europepmc +2 more sources
Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf +7 more
wiley +1 more source
Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives. [PDF]
Häner GM +7 more
europepmc +1 more source
One day of environment‐induced heat stress causes injury to the murine kidney
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths +3 more
wiley +1 more source
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source

