Results 31 to 40 of about 761,638 (295)

Regulated inositol synthesis is critical for balanced metabolism and development in Drosophila melanogaster

open access: yesBiology Open, 2021
Myo-inositol is a precursor of the membrane phospholipid, phosphatidylinositol (PI). It is involved in many essential cellular processes including signal transduction, energy metabolism, endoplasmic reticulum stress, and osmoregulation.
Maria J. Rivera   +4 more
doaj   +1 more source

SnapShot: Inositol Phosphates

open access: yesCell, 2010
Inositol diphosphates can transfer phosphatenonenzymatically to phosphoserine to generate diphosphate modi˜ed proteinsIP6K1 (KCS1) generated inositol diphosphatesare required for proper regulation of telomere lengthIpk2 regulates activity of Swi/Snf and Ino80chromatin-remodeling complexes in yeastIP6K1 (KCS1) is required for proper vacuole morphology ...
Hatch, Ace J., York, John D.
openaire   +2 more sources

Has Inositol Played Any Role in the Origin of Life? [PDF]

open access: yes, 2017
Phosphorus, as phosphate, plays a paramount role in biology. Since phosphate transfer reactions are an integral part of contemporary life, phosphate may have been incorporated into the initial molecules at the very beginning.
Saiardi, A
core   +1 more source

Metabolic Consequences of Polyphosphate Synthesis and Imminent Phosphate Limitation

open access: yesmBio, 2023
Cells stabilize intracellular inorganic phosphate (Pi) to compromise between large biosynthetic needs and detrimental bioenergetic effects of Pi.
Geun-Don Kim   +3 more
doaj   +1 more source

Effect of Phytase on In Vitro Hydrolysis of Phytate and the Formation of myo-Inositol Phosphate Esters in Various Feed Materials.

open access: yesJournal of Agricultural and Food Chemistry, 2019
Phytase is commonly used as a feed enzyme in monogastric animals to increase the bioavailability of phytate phosphorus and other nutrients. The accumulation of myo-inositol phosphate intermediates during phytate degradation in various segments of the ...
J. Hirvonen   +5 more
semanticscholar   +1 more source

Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition [PDF]

open access: yes, 2010
Inositol phosphates (InsPs) are signaling molecules with multiple roles in cells. In particular Graphic (InsP6) is involved in mRNA export and editing or chromatin remodeling among other events.
Agarwal   +35 more
core   +2 more sources

Degradation of phytate by the 6-phytase from Hafnia alvei: a combined structural and solution study. [PDF]

open access: yesPLoS ONE, 2013
Phytases hydrolyse phytate (myo-inositol hexakisphosphate), the principal form of phosphate stored in plant seeds to produce phosphate and lower phosphorylated myo-inositols.
Antonio Ariza   +12 more
doaj   +1 more source

Arabidopsis inositol phosphate kinases, IPK1 and ITPK1, constitute a metabolic pathway in maintaining phosphate homeostasis

open access: yesbioRxiv, 2018
Emerging studies have implicated a close link between inositol phosphate (InsP) metabolism and cellular phosphate (Pi) homeostasis in eukaryotes; however, whether a common InsP species is deployed as an evolutionarily conserved metabolic messenger to ...
Hui-Fen Kuo   +6 more
semanticscholar   +1 more source

A defective ABC transporter of the MRP family, responsible for the bean lpa1 mutation, affects the regulation of the phytic acid pathway, reduces seed myo-inositol and alters ABA sensitivity [PDF]

open access: yes, 2011
We previously identified the lpa1 (low phytic acid) 280-10 line that carries a mutation conferring a 90% reduction in phytic acid (InsP6) content. In contrast to other lpa mutants, lpa1(280-10) does not display negative pleiotropic effects.
Bollini, Roberto   +10 more
core   +1 more source

Harnessing 13C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00151d

open access: yesChemical Science, 2019
The analysis of inositol poly- and pyrophosphates, an important group of eukaryotic messengers, is enabled by applying 13C-labeled inositol.
Robert K. Harmel   +5 more
semanticscholar   +1 more source

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