Results 21 to 30 of about 71,946 (261)

Metabolic Consequences of Polyphosphate Synthesis and Imminent Phosphate Limitation

open access: yesmBio, 2023
Cells stabilize intracellular inorganic phosphate (Pi) to compromise between large biosynthetic needs and detrimental bioenergetic effects of Pi.
Geun-Don Kim   +3 more
doaj   +1 more source

Binding of inositol phosphates to arrestin [PDF]

open access: yesFEBS Letters, 1991
Arrestin binds to phosphorylated rhodopsin in its light‐activated form (metarhodopsin II), blocking thereby its interaction with the G‐protein, transducin. In this study, we show that highly phosphorylated forms of inositol compete against the arrestin‐rhodopsin interaction.
Palczewski, Krzysztof   +4 more
openaire   +2 more sources

Degradation of phytate by the 6-phytase from Hafnia alvei: a combined structural and solution study. [PDF]

open access: yesPLoS ONE, 2013
Phytases hydrolyse phytate (myo-inositol hexakisphosphate), the principal form of phosphate stored in plant seeds to produce phosphate and lower phosphorylated myo-inositols.
Antonio Ariza   +12 more
doaj   +1 more source

SnapShot: Inositol Phosphates

open access: yesCell, 2010
Inositol diphosphates can transfer phosphatenonenzymatically to phosphoserine to generate diphosphate modi˜ed proteinsIP6K1 (KCS1) generated inositol diphosphatesare required for proper regulation of telomere lengthIpk2 regulates activity of Swi/Snf and Ino80chromatin-remodeling complexes in yeastIP6K1 (KCS1) is required for proper vacuole morphology ...
Hatch, Ace J., York, John D.
openaire   +2 more sources

Inositols in Insulin Signaling and Glucose Metabolism

open access: yesInternational Journal of Endocrinology, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Arturo Bevilacqua, Mariano Bizzarri
doaj   +1 more source

A Gas Chromatography-Mass Spectrometry-Based Two Stage Assay for Measurement of in vitro myo-Inositol 3-phosphate Synthase (INO1) Activity

open access: yesBio-Protocol, 2015
This method describes an in vitro assay for measuring INO1 enzyme activity (the conversion of glucose 6-phosphate to myo-inositol 3-phosphate) in cell-free extracts. The method was first described for Plasmodium falciparum cells in MacRae et al.
James MacRae, Malcolm McConville
doaj   +1 more source

Countercurrent distribution of inositol lipids of plant seeds

open access: yesJournal of Lipid Research, 1969
The inositol lipids of plant seeds consist of phosphatidyl inositol, the phytoglycolipids, and a previously uncharacterized ceramide-phosphate-polysaccharide. These three species have been separated from each other and from the common glycerophosphatides
H.E. Carter, A. Kisic
doaj   +1 more source

A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis

open access: yesMetabolites, 2021
Phosphate is a major plant macronutrient and low phosphate availability severely limits global crop productivity. In Arabidopsis, a key regulator of the transcriptional response to low phosphate, phosphate starvation response 1 (PHR1), is modulated by a ...
Eric S. Land   +7 more
doaj   +1 more source

Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis

open access: yesNature Communications, 2021
Plants regulate phosphate homeostasis via the interaction of PHR transcription factors with SPX receptors bound to inositol pyrophosphate signaling molecules.
Martina K. Ried   +11 more
doaj   +1 more source

The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management

open access: yesFrontiers in Endocrinology, 2021
Myo-Inositol (MYO) is the most abundant stereoisomer of inositols’ family, cyclic polyols with 6 hydroxyl groups. Myo-Inositol has a relevant role in thyroid function and autoimmune diseases, as a precursor of phosphoinositides that takes part in the ...
Salvatore Benvenga   +7 more
doaj   +1 more source

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