Results 61 to 70 of about 761,638 (295)

How consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group? [PDF]

, 2015
This work was financially support by a Marie Curie Initial Training Network grant, “Understanding the evolutionary origin of biological diversity” (ITN-2008–213780 SPECIATION), grants from the Academy of Finland to A.H.
A Hoikkala, A Laiho, A Martin, A Sasson, AA Hoffmann, AL Majumder, AR McCune, B Katz, BJ Sinclair, C Canestro, CJ Reaume, CP Downes, D Arbuthnott, D Bell-Pedersen, D J Parker, DW Huang, DW Huang, FA Loewus, H Colinet, H Colinet, HA MacMillan, J Overgaard, J Zhang, JR Hazel, K Xu, KB Storey, KY Xu, L Kivivuori, L Vesala, L Vesala, L Vesala, LH Throckmorton, M G Ritchie, M Kankare, M Kim, M Reis, M Watanabe, M Watanabe, MC Magnone, MD Robinson, MD Robinson, MJ Fitzpatrick, MK Jones, MV Rockman, NM Teets, PR Senthilan, PW Hochachka, R David, R Morales-Hojas, R Niwa, RE Lee, RE Lee, RM Robich, RW Salt, S Anders, S Fowler, S Sahar, S Tweedie, V Kellermann, V Kostal, V Koštál, V Koštál, Vr Koštál, W Block, W Huang, WJ Heitler, WL Shen, X Huang, XL Guan, Y Benjamini, ZD Liu   +70 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]

, 2017
Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla, Jao, Li-En, Wente, Susan R   +2 more
core   +1 more source

Hydrolysis of phytate and formation of inositol phosphate isomers without or with supplemented phytases in different segments of the digestive tract of broilers

Journal of Nutritional Science, 2015
The objective was to characterise degradation of myo-inositol 1,2,3,4,5,6-hexakis (dihydrogen phosphate) (InsP6) and formation of inositol phosphate (InsP) isomers in different segments of the broiler digestive tract.
E. Zeller, M. Schollenberger, I. Kühn, M. Rodehutscord   +3 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Detection of Inositol Polyphosphates by Polyacrylamide Gel Electrophoresis (PAGE) under Apoptotic Conditions in Cultured SW480 Cells [PDF]

, 2010
Inositol phosphates are naturally occurring compounds that regulate diverse cellular processes including apoptosis. Apoptosis is a mechanism by which cells undergo natural death to maintain cellular homeostasis.
Agarwal, R., Ali, N., Hassen, S., Mohsin, R., Mumtaz, H., Zafar, M. K.   +5 more
core   +1 more source

Deciphering interplay between Salmonella invasion effectors [PDF]

, 2007
Bacterial pathogens have evolved a specialized type III secretion system (T3SS) to translocate virulence effector proteins directly into eukaryotic target cells.
AL Rozelle, BB Finlay, CE Stebbins, CM Collazo, D Vignjevic, D Zhou, D Zhou, EC Boyle, EJ McGhie, EJ McGhie, FA Norris, H Guillou, J Chang, J Chang, JB Morris, JC Patel, JC Patel, JE Galan, JE Galan, K Muramoto, K Niebuhr, K Ohnishi, LC Brawn, LD Hernandez, LD Hernandez, LM Chen, MC Schlumberger, MJ Garner, MR Terebiznik, P Cossart, P Dean, R Rohatgi, Ralph R. Isberg, RD Hayward, RD Hayward, RD Hayward, RD Hayward, Richard D. Hayward, RJ Cain, Robert J. Cain, S Andrews, S Stender, T Kubori, Vassilis Koronakis, WD Hardt, Y Fu   +45 more
core   +5 more sources

M–O–C Catalysts: Copper Single Atoms Supported on Oxocarbon Covalent Networks as Electrocatalysts for Glycerol Oxidation to Formic Acid

Angewandte Chemie, EarlyView.
We introduce a new class of single‐atom electrocatalysts based on oxygen‐coordinated metal sites embedded in oxocarbon networks (M–O–C), alternative to traditional M–N–C materials. A Cu–O–C catalyst derived from oxocarbon precursors exhibits highly dispersed Cu single atoms and delivers faster glycerol oxidation kinetics and higher formate selectivity ...
Xinyue Zheng, Teodor Jianu, Yizhou Dai, Anastaios Orestis Grammennos, Nadezda V. Tarakina, Fernando Igoa Saldaña, Jiatu Liu, Zhihong Tian, Markus Antonietti, Mateusz Odziomek   +9 more
wiley   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors [PDF]

, 1996
Signal transduction pathways that mediate C5a and fMet-Leu-Phe (fMLP)-induced pertussis toxin (PTx)-sensitive activation of phospholipase C (PLC) have been investigated using a cotransfection assay system in COS-7 cells.
Jiang, Huiping, Kuang, Yanan, Simon, Melvin I., Smrcka, Alan, Wu, Dianqing, Wu, Yanping   +5 more
core   +1 more source