Oxytocin at physiological concentrations evokes adrenocorticotropin (ACTH) release from corticotrophs by increasing intracellular free calcium mobilized mainly from intracellular stores. Oxytocin displays synergistic or additive effects on ACTH-releasing factor or arginine vasopressin-induced ACTH secretion, respectively [PDF]
, 1992 The potency of oxytocin (OT) in evoking ACTH secretion by isolated, superfused rat adenohypophyseal corticotrophs and its enhancement by CRF and arginine vasopressin (AVP) were analyzed.
Dayanithi, G. +3 more
core +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Inositol, neural tube closure and the prevention of neural tube defects [PDF]
, 2016 Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition.
Copp, AJ, Greene, ND, Leung, KY
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The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles [PDF]
, 2016 Anna Frej +11 more
openalex +1 more source
Hydrolysis of precipitated phytate by three distinct families of phytases [PDF]
, 2006 While genetically modified plants that secrete histidine acid phosphatases (HAPs), β-propeller phytases (BPPs) and purple acid phosphatases (PAPs) have been shown to assimilate soluble phytate, little is known about whether these plants have the ability ...
Leung, A, Leung, C, Lim, BL, Tang, J
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Microbiology and Immunology, EarlyView.ABSTRACT Among the three prion strains of bovine spongiform encephalopathy (BSE), classical BSE (C‐BSE) prions are known causative agents of variant Creutzfeldt–Jakob disease. By contrast, human infections with L‐type (L‐) or H‐type (H‐) BSE prions have not been reported.
Ken'ichi Hagiwara +8 more
wiley +1 more source
Inositol Phosphates and Derivatives [PDF]
, 1991 Biochemistry, Stereochemistry, and Nomenclature of the Inositol Phosphates Phosphoinositides and Their Stimulated Breakdown Enantiospecific Synthesis and Ca^2]+-Release Activities of Some Inositol Polyphosphates and Their Derivatives Synthesis of Inositol Polyphosphates and Their Derivatives Synthesis of myo-Inositol Polyphosphates Preparation of ...
openaire +1 more source
Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor. [PDF]
, 1992 We recently isolated a cDNA clone encoding a functional platelet thrombin receptor that defined a unique mechanism of receptor activation. Thrombin cleaves its receptor's extracellular amino terminal extension, unmasking a new amino terminus that ...
Coughlin, SR +3 more
core +1 more source