Results 111 to 120 of about 27,445 (272)

Inositol Phosphates: A Remarkably Versatile Enzyme [PDF]

Current Biology, 2002
Ins(3,4,5,6)P(4) is an inhibitor of Ca(2+)-activated Cl(-) channels, but further understanding has been hindered by ignorance of how it is made in cells. It now transpires that one protein with ATP-dependent kinase and phosphatase activities interconverts Ins(3,4,5,6)P(4) and Ins(1,3,4,5,6)P(5), as well as several other inositol polyphosphates.
openaire   +2 more sources

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer

Frontiers in Oncology, 2017
Calcium is a critical regulator of cell death pathways. One of the most proximal events leading to cell death is activation of plasma membrane and endoplasmic reticulum-resident calcium channels.
Jessica J. Chen, Darren Boehning
doaj   +1 more source

Does visual cortex lactate increase following photic stimulation in migraine without aura patients?: a functional 1H-MRS study [PDF]

, 2011
Proton magnetic resonance spectroscopy ((1)H-MRS) has been used in a number of studies to assess noninvasively the temporal changes of lactate (Lac) in the activated human brain.
Reyngoudt, Harmen, Paemeleire, Koen, Dierickx, Anneloor, Descamps, Benedicte, Vandemaele, Pieter, De Deene, Yves, Achten, Eric   +6 more
core   +2 more sources

Impact of spring rape varieties on protein extraction from press cake, emulsifying properties and antinutrient content

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Rapeseed is the second most cultivated oilseed globally after soybean and a protein‐rich press cake is generated after liberation of the oil. However, its use in food applications is limited by high levels of anti‐nutrients such as glucosinolates and phytic acid. Although differences between botanical varieties are known, controlled
Cecilia Ahlström, Evangelia Papagianni, Eu Sheng Wang, Inger‐Cecilia Mayer Labba, Ann‐Sofie Sanberg, Emil Andersson, Johan Thuvander, Karolina Östbring   +7 more
wiley   +1 more source

LC‐ICP‐MS analysis of inositol phosphate isomers in soil offers improved sensitivity and fine‐scale mapping of inositol phosphate distribution

Methods in Ecology and Evolution
Organic forms of phosphorus (P) prevail in soils and their quantification is vital to better understand global biogeochemical cycles. P speciation in soil is commonly assessed by 31P NMR spectroscopy of sodium hydroxide‐EDTA (NaOH‐EDTA) extracts.
Joseph J. Carroll, Colleen Sprigg, Graham Chilvers, Ignacio Delso, Megan Barker, Filipa Cox, David Johnson, Charles A. Brearley   +7 more
doaj   +1 more source

Analysis of Dictyostelium discoideum Inositol Pyrophosphate Metabolism by Gel Electrophoresis. [PDF]

, 2014
The social amoeba Dictyostelium discoideum was instrumental in the discovery and early characterization of inositol pyrophosphates, a class of molecules possessing highly-energetic pyrophosphate bonds.
Chubb, JR, Gaspari, M, Livermore, T, Pisani, F, Rose, G, Saiardi, A   +5 more
core  

Analysis of weighted co-regulatory networks in maize provides insights into new genes and regulatory mechanisms related to inositol phosphate metabolism [PDF]

, 2016
Sub-network 1 and 2 of “magenta2”, node annotation.
Chunyi Zhang, Ling Jiang, Qianqian Zhao, Rumei Chen, Shaojun Zhang, Shuai Ma, Wenzhu Yang, Xiaojin Zhou, Xiaoqing Liu, Ye Li, Yunliu Fan   +10 more
core   +6 more sources

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon, Meng Gu, Ralph Hurd, Kirk Riemer, Frank Hanley, Daniel Spielman   +5 more
wiley   +1 more source