Results 101 to 110 of about 14,137 (280)

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives

Natural Product Reports, 2007
This review highlights inositol polyphosphate- and phosphatidylinositol-based small molecule probes that have advanced our understanding of intracellular signalling.
Conway, Stuart J., Miller, Gavin J.; id_orcid 0000-0001-6533-3306   +1 more
openaire   +3 more sources

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

The investigation of antinutritional factors in Phaseolus vulgaris. Environmental and varietal differences [PDF]

Biotechnologie, Agronomie, Société et Environnement, 1999
This study enables us to indicate that the oligosaccharide raffinose family, phytate, saponin and lectin contents of P. vulgaris are clearly influenced by both environmental and genetics factors.
Burbano C., Muzquiz M., Ayet G., Pedrosa M.M., Cuadrado C.   +4 more
doaj  

Tumour suppressor PTEN activity is differentially inducible by myo-inositol phosphates. [PDF]

J Cell Mol Med, 2023
Grzymajlo K, El Hafny-Rahbi B, Kieda C.
europepmc   +1 more source

Endothelin-Induced Sarcoplasmic Reticulum Calcium Depletion Waves in Vascular Smooth Muscle Cells

, 2011
Agonist-stimulated waves of elevated cytoplasmic Ca2+ concentration ([Ca2+]i ) regulate blood vessel tone and vasomotion in vascular smooth muscle. Previous studies employing cytoplasmic Ca2+ indicators revealed that these Ca2+ waves were generated by a ...
Cornelis van Breemen, Jeremy Hoskins, Arash Y. Tehrani, Mitra Esfandiarei, Yohan Choi, Nicola Fameli, Jeremy G. Hoskins, Arash Tehrani   +7 more
core   +1 more source

Interaction Between Nitrogen Forms, Phosphorus Forms, and Mineral Phases Drives Phosphorus Limitation and Uptake by Ryegrass in a Model System

Journal of Plant Nutrition and Soil Science, EarlyView.
Nitrogen addition shifts plant nutrition from nitrogen to phosphorus (P) limitation. Nitrate‐based nitrogen enhances P acquisition more effectively than ammonium through increased phosphatase activity, independently of pH changes. Organic P forms induce stronger P limitation than inorganic P.
Issifou Amadou, Michel‐Pierre Faucon, Josep Peñuelas, Jordi Sardans, David Houben   +4 more
wiley   +1 more source

Inositol Phosphates and Derivatives [PDF]

, 1991
Biochemistry, Stereochemistry, and Nomenclature of the Inositol Phosphates Phosphoinositides and Their Stimulated Breakdown Enantiospecific Synthesis and Ca^2]+-Release Activities of Some Inositol Polyphosphates and Their Derivatives Synthesis of Inositol Polyphosphates and Their Derivatives Synthesis of myo-Inositol Polyphosphates Preparation of ...
openaire   +1 more source

Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus

The EMBO Journal
Kinases that synthesize inositol phosphates (IPs) and pyrophosphates (PP-IPs) control numerous biological processes in eukaryotic cells. Herein, we extend this cellular signaling repertoire to viruses. We have biochemically and structurally characterized
Guangning Zong, Yann Desfougères, Paloma Portela-Torres, Yong-Uk Kwon, Adolfo Saiardi, Stephen B. Shears, Huanchen Wang   +6 more
doaj   +1 more source