Results 181 to 190 of about 14,137 (280)

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 557-567, August 2026.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon   +5 more
wiley   +1 more source

Cementum Attachment Protein‐Derived Peptides Modulate Brushite and Calcium Oxalate Crystallization In Vitro

open access: yesJournal of Peptide Science, Volume 32, Issue 8, August 2026.
Cementum attachment protein‐derived peptides adsorb to specific crystallographic faces of brushite and calcium oxalate, blocking calcium deposition. This phosphorylation‐enhanced modulation alters crystal growth under conditions in vitro, leading to the formation of irregular brushite crystals and rosette‐like calcium oxalate morphologies.
Alberto Mimila‐Cortes   +9 more
wiley   +1 more source

Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes. [PDF]

open access: yesProc Natl Acad Sci U S A, 2017
Song ES   +8 more
europepmc   +1 more source

Pathomechanism of Fever‐Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC—Observations In Vitro and In Vivo

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun   +29 more
wiley   +1 more source

Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Transplanting the fecal microbiota of patients with lung injury into mice causes an increase in LPS in the mice's blood, thereby leading to chronic lung injury in the mice. Meanwhile, oral administration of vancomycin can enhance colonic butyrate metabolism and improve lung injury in mice.
Jianuo Chen   +9 more
wiley   +1 more source

Fibrinogen - a possible extracellular target for inositol phosphates. [PDF]

open access: yesMessenger (Los Angel), 2012
Grint T   +4 more
europepmc   +1 more source

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 4, Page 1002-1029, July 2026.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi   +8 more
wiley   +1 more source

Interactions of Plant Protein and Natural Colorant: A Structural and Functional Relationship of Broccoli Protein and Marigold Color Compounds

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Graphical representation of the interactions of the structural and functional relationships of broccoli flower protein (BFP) and marigold color compounds (MCC). This research examines BFP–MCC interactions of extracted marigold color, chemical composition, and functional attributes.
Fidele Benimana   +2 more
wiley   +1 more source

Astrocyte Mechanobiology: Linking Biomechanical Forces to Biochemical Signaling in the Central Nervous System

open access: yesGlia, Volume 74, Issue 7, July 2026.
Astrocytes are key sensors and transducers of biomechanical stimuli within the central nervous system. Astrocyte development is highly dependent on mechanical stimuli such as surrounding tissue stiffness and biomechanical strain. Mechanosensory pathways including integrins, connexins and pannexins, and mechanosensitive channels regulate astrocyte ...
Ana N. Strat   +3 more
wiley   +1 more source

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