Results 41 to 50 of about 30,119 (260)

Inositol metabolism as a broad-spectrum antiviral target

Frontiers in Microbiology
Inositol plays many important roles in cellular processes through its various derivatives including phosphatidylinositol phosphates. Viruses use phosphatidylinositol phosphates for their replication in multiple processes including entry, formation of ...
Kunlakanya Jitobaom, Kunlakanya Jitobaom, Prasert Auewarakul, Prasert Auewarakul   +3 more
doaj   +1 more source

The Impact of Mash pH and Exogenous Phosphorolytic Enzymes on the Release of Inositol Phosphates, Fermentable Sugars and Polypeptide Profile in the Technology of Buckwheat Beer

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology, 2022
The first - already published - stage of the project, which conducted optimization of the temperature mashing program, yielded promising results in the form of an increase in the pool of bioactive myo-inositol by 50% in buckwheat wort supplemented with ...
Robert DULIŃSKI, Dagmara PONIEWSKA
doaj   +1 more source

Inositols in Insulin Signaling and Glucose Metabolism [PDF]

, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
core   +1 more source

Tipping the scales:Lessons from simple model systems on inositol imbalance in neurological disorders [PDF]

, 2017
Inositol and inositol-containing compounds have signalling and regulatory roles in many cellular processes, suggesting that inositol imbalance may lead to wide-ranging changes in cellular functions.
Abe, Adley, Alberdi, Alers, Alzheimer’s Disease International, Anna D. Frej, Bachhawat, Belmaker, Berridge, Brickner, Buckmaster, Bélanger, Calker, Cataldi, Chang, Chang, Chang, Chang, Chang, Chiu, Cho, Clark, Clements, Cremona, Criollo, Croze, Culbertson, Das, Davanzo, Dean-Johnson, Deranieh, Deranieh, Deranieh, Di Daniel, Drion, Eickholt, Fajutrao, Felberbaum, Fenili, Ferruz, Fischbach, Fischer, Frej, Fu, Ghavami, Grant P. Otto, Greenberg, Griffith, Hartman, Hasegawa, Ho, Hoyer, Irvine, Jiang, Ju, Ju, Kaddurah-Daouk, Kamada, Keith, Kennedy, King, Kirshenbaum, Klopfenstein, Kollros, Konarzewska, Kosta, Kotaria, Kurnasov, Kwan, Lester, Lhuillier, Loewus, Looney, Lopes, Lystad, MacGregor, Macias, Majumder, Martin, Masaki, McKnight, McLaurin, McMahon, Meng, Mizushima, Mohammadpour, Murray, Nonaka, Nozadze, Ohnishi, Otto, O’Donnell, Parthasarathy, Pascente, Pattni, Pereira, Prieto, Puls, Qing, Randise-Hinchliff, Robin S.B. Williams, Sarkar, Saudek, Schewe, Schiebler, Sha, Shaldubina, Shaltiel, Shetty, Shi, Shimon, Silverstone, Singh, Solomonia, Solomonia, Solomonia, Steger, Stransky, Teo, Terbach, Toker, Trushina, Vaden, van Vliet, Vanhaesebroeck, Viard, Vogel, Wang, Warsh, Watanabe, Waugh, Wellard, Whiting, Williams, Williams, Wong, Wu, Wu, Xu, Yamagami, Zeng   +140 more
core   +1 more source

Detection of Inositol Polyphosphates by Polyacrylamide Gel Electrophoresis (PAGE) under Apoptotic Conditions in Cultured SW480 Cells [PDF]

, 2010
Inositol phosphates are naturally occurring compounds that regulate diverse cellular processes including apoptosis. Apoptosis is a mechanism by which cells undergo natural death to maintain cellular homeostasis.
Agarwal, R., Ali, N., Hassen, S., Mohsin, R., Mumtaz, H., Zafar, M. K.   +5 more
core   +1 more source

Inhibition of Subsets of G Protein-coupled Receptors by Empty Mutants of G Protein α Subunits in Go, G11, and G16 [PDF]

, 2000
We previously reported that the xanthine nucleotide binding Goα mutant, GoαX, inhibited the activation of Gi-coupled receptors. We constructed similar mutations in G11α and G16α and characterized their nucleotide binding and receptor interaction.
Gu, Lingjie, Simon, Melvin I., Yu, Bo
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phytic acid degradation by phytase – as viewed by 31P NMR and multivariate curve resolution [PDF]

, 2007
The 31P NMR method is a most direct and useful method to describe the degradation of phytic acid to lower inositol phosphates by the action of the enzyme phytase.
Engelsen, Søren Balling, Nielsen, Merete Møller, Viereck, Nanna   +2 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source