Results 111 to 120 of about 2,351 (231)

Polyphosphate Accumulation Is Determined by Zinc and Inositol in Saccharomyces cerevisiae

Yeast, Volume 42, Issue 11, Page 249-260, November 2025.
Zinc and inositol supplementation during phosphate starvation significantly enhances final polyphosphate levels in S. cerevisiae. ABSTRACT Polyphosphate (polyP) is an intriguing polymer with diverse biological and industrial applications. Chemical polyP production is energy‐intensive and limited in chain length at large‐scale production. Alternatively,
Alexander Deitert, Makarius Baier, Roy Eerlings, Jana Fees, Ailín Österlein Kück, Julia Repin, Philipp Demling, Lars M. Blank   +7 more
wiley   +1 more source

Detection of Inositol Polyphosphates by Polyacrylamide Gel Electrophoresis (PAGE) under Apoptotic Conditions in Cultured SW480 Cells [PDF]

, 2010
Inositol phosphates are naturally occurring compounds that regulate diverse cellular processes including apoptosis. Apoptosis is a mechanism by which cells undergo natural death to maintain cellular homeostasis.
Agarwal, R., Ali, N., Hassen, S., Mohsin, R., Mumtaz, H., Zafar, M. K.   +5 more
core   +1 more source

Exploring the Causal Relationship Between Blood Metabolites and Chronic Periodontitis: Insights From Genetic Causal Analysis

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT To investigate the potential bidirectional causal relationship between specific blood metabolites and chronic periodontitis using Mendelian randomisation (MR). A two‐sample bidirectional MR analysis was conducted. Data on 1400 blood metabolites were obtained from a genome‐wide association study involving 8299 participants.
Weilun Cai, Huaxuan Zhao, Panpan Wang, Xiao Chen, Yumeng Yang, Hongle Wu, Zehao Chen, Fuchun Fang, Wei Qiu   +8 more
wiley   +1 more source

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

Advanced Science, Volume 12, Issue 40, October 27, 2025.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu, Dongqin Ding, Huiying Wang, Xinyi Ren, Sang Yup Lee, Dawei Zhang   +5 more
wiley   +1 more source

The inositol pyrophosphate pathway in health and diseases [PDF]

Biological Reviews, 2017
ABSTRACTInositol pyrophosphates (IPPs) are present in organisms ranging from plants, slime moulds and fungi to mammals. Distinct classes of kinases generate different forms of energetic diphosphate‐containing IPPs from inositol phosphates (IPs). Conversely, polyphosphate phosphohydrolase enzymes dephosphorylate IPPs to regenerate the respective IPs ...
openaire   +2 more sources

Tipping the scales:Lessons from simple model systems on inositol imbalance in neurological disorders [PDF]

, 2017
Inositol and inositol-containing compounds have signalling and regulatory roles in many cellular processes, suggesting that inositol imbalance may lead to wide-ranging changes in cellular functions.
Abe, Adley, Alberdi, Alers, Alzheimer’s Disease International, Anna D. Frej, Bachhawat, Belmaker, Berridge, Brickner, Buckmaster, Bélanger, Calker, Cataldi, Chang, Chang, Chang, Chang, Chang, Chiu, Cho, Clark, Clements, Cremona, Criollo, Croze, Culbertson, Das, Davanzo, Dean-Johnson, Deranieh, Deranieh, Deranieh, Di Daniel, Drion, Eickholt, Fajutrao, Felberbaum, Fenili, Ferruz, Fischbach, Fischer, Frej, Fu, Ghavami, Grant P. Otto, Greenberg, Griffith, Hartman, Hasegawa, Ho, Hoyer, Irvine, Jiang, Ju, Ju, Kaddurah-Daouk, Kamada, Keith, Kennedy, King, Kirshenbaum, Klopfenstein, Kollros, Konarzewska, Kosta, Kotaria, Kurnasov, Kwan, Lester, Lhuillier, Loewus, Looney, Lopes, Lystad, MacGregor, Macias, Majumder, Martin, Masaki, McKnight, McLaurin, McMahon, Meng, Mizushima, Mohammadpour, Murray, Nonaka, Nozadze, Ohnishi, Otto, O’Donnell, Parthasarathy, Pascente, Pattni, Pereira, Prieto, Puls, Qing, Randise-Hinchliff, Robin S.B. Williams, Sarkar, Saudek, Schewe, Schiebler, Sha, Shaldubina, Shaltiel, Shetty, Shi, Shimon, Silverstone, Singh, Solomonia, Solomonia, Solomonia, Steger, Stransky, Teo, Terbach, Toker, Trushina, Vaden, van Vliet, Vanhaesebroeck, Viard, Vogel, Wang, Warsh, Watanabe, Waugh, Wellard, Whiting, Williams, Williams, Wong, Wu, Wu, Xu, Yamagami, Zeng   +140 more
core   +1 more source

Dinucleoside Polyphosphates in Cellular Signaling: Function and Evolution Across Life

BioEssays, Volume 47, Issue 10, October 2025.
Although discovered more than 50 years ago, the cellular functions of Ap4A and related dinucleotides remain largely enigmatic. To address this knowledge gap, we organized a conference showcasing recent research that highlights the critical role of Ap4A as a global regulator across all domains of life.
Gert Bange, Jennifer N. Andexer, Henning J. Jessen, Johannes Freitag, Sonja‐Verena Albers, Jan Pané‐Farré   +5 more
wiley   +1 more source

Natural Products Containing ‘Rare’ Organophosphorus Functional Groups [PDF]

, 2019
Phosphorous-containing molecules are essential constituents of all living cells. While the phosphate functional group is very common in small molecule natural products, nucleic acids, and as chemical modification in protein and peptides, phosphorous can ...
Bains, William, Petkowski, Janusz Jurand, Seager, Sara   +2 more
core   +1 more source

UFMylation System: Biological Functions, Molecular Mechanisms, Diseases, and Drug Discovery

MedComm, Volume 6, Issue 10, October 2025.
UFMylation, a novel ubiquitin‐like modification, plays an essential role in various cellular processes, such as the immune response, DNA damage repair, unfolded protein response (UPR), autophagy, endoplasmic reticulum (ER)‐phagy, stem cell self‐renewal, apoptosis, and metastasis.
Huiyan Li, Fei Meng, Junjie Liang, Yijie Wang, Changliang Shan, Yan Chen   +5 more
wiley   +1 more source

Caractérisation -par spectrométrie RMN du 31P- de constituants phosphatés extraits de sols de rizières malgaches [PDF]

, 1989
Les composés phosphatés de six sols de rizières, riches en matière organique, originaires de Madagascar ont été extraits par une solution sodique. Ces composés ont été déterminés soit par une analyse chimique globale, soit par une spectrométrie RMN du ...
Fardeau, J.C., Forster, J.C., Rakotoasimbola, S., Zech, W.   +3 more
core