Results 101 to 110 of about 751 (180)
, 2023 Inositol phosphates and their pyrophosphorylated derivatives are responsive to the phosphate supply and are agents of phosphate homeostasis and other aspects of physiology. It seems likely that the enzymes that interconvert these signals work against the
Riley, Andrew M +14 more
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Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability
Molecular BrainInositol pyrophosphates are key signaling molecules that regulate diverse neurobiological processes. We previously reported that the inositol pyrophosphate 5-InsP7, generated by inositol hexakisphosphate kinase 1 (IP6K1), governs the degradation of Na+/K+
Hongfu Jin +5 more
doaj +1 more source
Cell Reports, 2013 Cells respond to stress and starvation by adjusting their growth rate and enacting stress defense programs. In eukaryotes this involves inactivation of TORC1, which in turn triggers downregulation of ribosome and protein synthesis genes and upregulation ...
Jeremy Worley +2 more
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[PSI+] prion propagation is controlled by inositol polyphosphates
, 2017 Significance The [PSI+] prion of baker’s yeast is a filamentous polymer (amyloid) of the Sup35 protein, producing readthrough of translation termination and different degrees of growth slowing, depending on the prion variant.
Herman K. Edskes +3 more
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Kcs1 and Vip1: The Key Enzymes behind Inositol Pyrophosphate Signaling in Saccharomyces cerevisiae
BiomoleculesThe inositol pyrophosphate pathway, a complex cell signaling network, plays a pivotal role in orchestrating vital cellular processes in the budding yeast, where it regulates cell cycle progression, growth, endocytosis, exocytosis, apoptosis, telomere ...
Larisa Ioana Gogianu +2 more
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When worlds collide: inositol pyrophosphates and phosphoinositides intersect at the plasma membrane.
, 2013 Highly phosphorylated inositol pyrophosphates are present in the cells of many organisms such as yeast, Dictyostelium and mammals. They can act as signal molecules in growth factor and insulin signalling both in cultured cells and in intact mice.
Elong Edimo, William's +1 more
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A linear pathway for inositol pyrophosphate metabolism revealed by 18O labeling and model reduction.
PLoS Computational BiologyThe homeostasis of intracellular inorganic phosphate is essential for eukaryotic metabolism and is regulated by the INPHORS signalling pathway, which employs inositol pyrophosphates (IPPs) as key intermediary messengers.
Jacques Hermes +6 more
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, 2021 Ph.D.Inositol pyrophosphates are high energy signaling molecules found across eukaryotes that are important for diverse cellular processes like phosphate homeostasis, the immune response, fungal pathogenicity, endocytosis, energy homeostasis and stress ...
Morrissette, Victoria
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