Results 81 to 90 of about 751 (180)
Inositol Pyrophosphate Metabolism Regulates Presynaptic Vesicle Cycling at Central Synapses
iScience, 2020 Summary: The coordination of synaptic vesicle exocytosis and endocytosis supports neurotransmitter release from presynaptic terminals. Although inositol pyrophosphates, such as 5-diphosphoinositol pentakisphosphate (5-IP7), are versatile signaling ...
Seung Ju Park +6 more
doaj +1 more source
Rh‐Catalyzed Enantioselective and Regioselective Addition of Phosphinoylacetic Acid to Allenes
ChemCatChem, Volume 18, Issue 12, 26 June 2026.A highly efficient, versatile, and universal protocol to chiral branched allylic esters is demonstrated via Rh‐catalyzed asymmetric addition of phosphinoylacetic acid to allenes in a regio‐ and enantioselective fashion. ABSTRACT A Rh‐catalyzed enantioselective addition of phosphinoylacetic acid to allenes is developed, delivering branched allylic ...
Yanxin Jiang +4 more
wiley +1 more source
Developing Dictyostelium discoideum as a model to study the synthesis and metabolism of inositol pyrophosphates and inorganic polyphosphate [PDF]
, 2016 Inositol pyrophosphates and inorganic polyphosphate (polyP) represent two of the most phosphate-rich molecules in the cell. However, the synthesis, metabolism and function of these “high-energy” molecules are not well understood.
Livermore, TM
core
, 2013 Several studies have demonstrated the activation of phosphoinositide-specific phospholipase C (Plc) in nuclei of mammalian cells during synchronous progression through the cell cycle, but the downstream targets of Plc-generated inositol 1,4,5 ...
York, John D. +3 more
core +1 more source
The Key Role of IP6K: A Novel Target for Anticancer Treatments?
Molecules, 2020 Inositol and its phosphate metabolites play a pivotal role in several biochemical pathways and gene expression regulation: inositol pyrophosphates (PP-IPs) have been increasingly appreciated as key signaling modulators.
Mirko Minini +3 more
doaj +1 more source
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, Volume 2, Issue 2, June 2026.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Inositol Pyrophosphate Pathways and Mechanisms: What Can We Learn from Plants?
Molecules, 2020 The ability of an organism to maintain homeostasis in changing conditions is crucial for growth and survival. Eukaryotes have developed complex signaling pathways to adapt to a readily changing environment, including the inositol phosphate (InsP ...
Caitlin Cridland, Glenda Gillaspy
doaj +1 more source
Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing
The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz +5 more
wiley +1 more source
Functional Ecology, Volume 40, Issue 6, Page 1790-1808, June 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant‐ and microbial‐derived residues constitute the primary sources of soil organic carbon (SOC) in grassland ecosystems. However, their differential responses to chronic nitrogen (N) enrichment and the depth‐dependent mechanisms governing their accumulation remain ...
Xiaobo Yuan +19 more
wiley +1 more source
Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processes [PDF]
Advances in Enzyme Regulation, 2010 Inositol phosphates and inositol pyrophosphates are small molecule metabolites that play important roles in nuclear processes such as transcription control, mRNA export and DNA repair. On this wonderful occasion of the fiftieth anniversary of the Advances in Enzyme Regulation conference, it is a privilege to participate through presenting recent ...
Marco M, Tsui, John D, York
openaire +2 more sources