Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe
Journal of Fungi, 2022 Inositol pyrophosphates (IPPs) comprise a specific class of signaling molecules that regulate central biological processes in eukaryotes. The conserved Vip1/PPIP5K family controls intracellular IP8 levels, the highest phosphorylated form of IPPs present ...
Natascha Andrea Kuenzel +6 more
doaj +1 more source
Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification
Plant Biotechnology Journal, Volume 24, Issue 10, Page 5510-5525, October 2026.ABSTRACT Terpenes constitute the largest and most structurally diverse class of plant secondary metabolites, with critical roles in plant‐environment interactions and broad industrial applications. Although nuclear genome engineering of terpene pathways has been extensively explored, chloroplast genome engineering remains largely undeveloped, with most
Alessandro Occhialini +6 more
wiley +1 more source
Developing Dictyostelium discoideum as a model to study the synthesis and metabolism of inositol pyrophosphates and inorganic polyphosphate [PDF]
, 2016 Inositol pyrophosphates and inorganic polyphosphate (polyP) represent two of the most phosphate-rich molecules in the cell. However, the synthesis, metabolism and function of these “high-energy” molecules are not well understood.
Livermore, TM
core
How inositol pyrophosphates control cellular phosphate homeostasis? [PDF]
, 2012 Phosphorus in his phosphate PO(4)(3-) configuration is an essential constituent of all life forms. Phosphate diesters are at the core of nucleic acid structure, while phosphate monoester transmits information under the control of protein kinases and ...
Saiardi, A
core
[PSI+] prion propagation is controlled by inositol polyphosphates
, 2017 Significance The [PSI+] prion of baker’s yeast is a filamentous polymer (amyloid) of the Sup35 protein, producing readthrough of translation termination and different degrees of growth slowing, depending on the prion variant.
Herman K. Edskes +3 more
core +1 more source
Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis
, 2018 Inositol pyrophosphates such as 5-diphosphoinositol pentakisphosphate (5-IP7) are highly energetic inositol metabolites containing phosphoanhydride bonds. Although inositol pyrophosphates are known to regulate various biological events, including growth,
Tae-Young Yoon +14 more
core +1 more source
Correction: Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response. [PDF]
PLoS Pathogens, 2014 doaj +3 more sources
BMC Biology, 2021 Background Inositol pyrophosphates (PP-InsPs) are high-energy derivatives of inositol, involved in different signalling and regulatory responses of eukaryotic cells.
Anuj Shukla +12 more
doaj +1 more source
The role of inositol pyrophosphates in the DNA damage response [PDF]
, 2021 Objetivo: Analisar a influência dos metabólitos do inositol, especialmente dos pirofosfatos de inositol, na resposta ao dano de DNA na levedura Saccharomyces cerevisiae.
Jekabson, Rafaella [UNIFESP]
core
Inositol Pyrophosphate Metabolism Regulates Presynaptic Vesicle Cycling at Central Synapses
iScience, 2020 Summary: The coordination of synaptic vesicle exocytosis and endocytosis supports neurotransmitter release from presynaptic terminals. Although inositol pyrophosphates, such as 5-diphosphoinositol pentakisphosphate (5-IP7), are versatile signaling ...
Seung Ju Park +6 more
doaj +1 more source