Results 71 to 80 of about 751 (180)

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

Pest Management Science, Volume 82, Issue 7, Page 6387-6398, July 2026.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest, Marianne Bessette, Geneviève Gagnon, Sandra Flores‐Mejia, Brahim Soufiane, Marie‐Claire Goulet, Dominique Michaud   +6 more
wiley   +1 more source

Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae

, 2015
Ribosome biogenesis is an essential cellular process regulated by the metabolic state of a cell. We examined whether inositol pyrophosphates, energy-rich derivatives of inositol that act as metabolic messengers, play a role in ribosome synthesis in the ...
Thampatty, Sitalakshmi R., Unnikannan, C. P., Manorama, R., Bhandari, Rashna, Thota, Swarna Gowri   +4 more
core   +1 more source

Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP₇

Biomolecules, 2023
Inositol pyrophosphates (PP-InsPs); are a functionally diverse family of eukaryotic molecules that deploy a highly-specialized array of phosphate groups as a combinatorial cell-signaling code.
Soumyadip Sahu, Jacob Gordon, Chunfang Gu, Mack Sobhany, Dorothea Fiedler, Robin E. Stanley, Stephen B. Shears   +6 more
doaj   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

Inositol Pyrophosphates as Versatile Metabolic Messengers

Annual Review of Biochemistry
Discovered in 1993, inositol pyrophosphates are evolutionarily conserved signaling metabolites whose versatile modes of action are being increasingly appreciated. These include their emerging roles as energy regulators, phosphodonors, steric/allosteric regulators, and G protein–coupled receptor messengers.
Latika, Nagpal, Sining, He, Feng, Rao, Solomon H, Snyder   +3 more
openaire   +2 more sources

Inositol pyrophosphates modulate hydrogen peroxide signalling

Biochemical Journal, 2009
Inositol pyrophosphates are involved in a variety of cellular functions, but the specific pathways and/or downstream targets remain poorly characterized. In the present study we use Saccharomyces cerevisiae mutants to examine the potential roles of inositol pyrophosphates in responding to cell damage caused by ROS (reactive oxygen species).
Onnebo, Sara Maria Nancy, Saiardi, Adolfo   +1 more
openaire   +3 more sources

Mass spectrometry analysis of inositol pyrophosphates purified from D. Discoideum cell extract.

, 2014
Gel purified inositol pyrophosphates (A) were subjected to mass spectrometry (B,C). The comparison of the m/z spectrum of IP7 (B) and IP8 (C) is shown. The peaks in the spectra describing inositol pyrophosphates purified from D.
Thomas Livermore (507716), Marco Gaspari (77912), Adolfo Saiardi (263859), Francesca Pisani (507715), Giuseppina Rose (80339), Jonathan Robert Chubb (507717)   +5 more
core   +1 more source

Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair [PDF]

, 2013
Inositol pyrophosphates, such as diphosphoinositol pentakisphosphate (IP7), are water-soluble inositol phosphates that contain high energy diphosphate moieties on the inositol ring.
Sengupta, Sagar, Jadav, Rathan S., Chanduri, Manasa V. L., Bhandari, Rashna   +3 more
core   +1 more source

Wheat inositol pyrophosphate kinase TaVIH2-3B modulates cell-wall composition and drought tolerance in Arabidopsis

BMC Biology, 2021
Background Inositol pyrophosphates (PP-InsPs) are high-energy derivatives of inositol, involved in different signalling and regulatory responses of eukaryotic cells.
Anuj Shukla, Mandeep Kaur, Swati Kanwar, Gazaldeep Kaur, Shivani Sharma, Shubhra Ganguli, Vandana Kumari, Koushik Mazumder, Pratima Pandey, Hatem Rouached, Vikas Rishi, Rashna Bhandari, Ajay Kumar Pandey   +12 more
doaj   +1 more source

Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Brice Beauvais, Rajendra Rohokale, Sevin Mamputu, Ion Lupu, Zhongwu Guo, Sébastien Balieu   +5 more
wiley   +1 more source