Results 61 to 70 of about 38,827 (170)
Nature Communications, 2016 Photocaged inositol-pyrophosphates offer a tool to study cellular signalling, but their challenging synthesis has precluded any biological studies so far.
Igor Pavlovic +11 more
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Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century
Chemistry – A European Journal, EarlyView.This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza +2 more
wiley +1 more source
Inositol Phosphates and Synthesizing Enzymes: Implications in Neurodegenerative Disorders
BiomoleculesInositol is a vital sugar molecule involved in numerous signaling pathways required for cellular homeostasis and cell survival. Myo-inositol and its phospho-derivatives, inositol phosphates (IPs), are the most prevalent forms of inositol found in living ...
Chisom J. Onu +4 more
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Inositol polyphosphates regulate and predict yeast pseudohyphal growth phenotypes.
PLoS Genetics, 2018 Pseudohyphal growth is a nutrient-regulated program in which budding yeast form multicellular filaments of elongated and connected cells. Filamentous growth is required for virulence in pathogenic fungi and provides an informative model of stress ...
Kaitlyn L Norman +6 more
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Advanced Science, Volume 13, Issue 59, 23 October 2026.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 10, October 2026.We explored genomic signatures of balancing selection and selective sweep in the northern medaka, Oryzias sakaizumii in Japan by performing whole‐genome resequencing of wild individuals. In addition, we reevaluated the population genetic structure and admixture of Oryzias latipes and O.
Shingo Fujimoto +9 more
wiley +1 more source
Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis
Molecules, 2020 Chronic inflammation is one of the most common and well-recognized risk factors for human cancer, including colon cancer. Inflammatory bowel disease (IBD) is defined as a longstanding idiopathic chronic active inflammatory process in the colon, including
Samuel E. Weinberg +4 more
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The emerging roles of inositol pyrophosphates in eukaryotic cell physiology
, 2015 Inositol pyrophosphates are water soluble derivatives of inositol that contain pyrophosphate or diphosphate moieties in addition to monophosphates. The best characterised inositol pyrophosphates, are IP7 (diphosphoinositol pentakisphosphate or PP-IP5 ...
Thota, Swarna Gowri, Bhandari, Rashna
core +1 more source
The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export [PDF]
, 2019 Phosphate's central role in most biochemical reactions in a living organism requires carefully maintained phosphate homeostasis. Although phosphate homeostasis in mammals has long been studied at the organismal level, the intracellular mechanisms ...
Jessen, HJ, Saiardi, A, Wilson, MS
core +3 more sources
Nitrogen Fertilization Temporarily Enhances Phosphatase Activity in a High‐P Loamy Sand
Journal of Plant Nutrition and Soil Science, Volume 189, Issue 5, Page 794-802, October 2026.ABSTRACT Background Efficient plant utilization of soil phosphorus (P) is essential to reduce dependence on mineral P fertilizers in intensive agriculture. Input of mineral nitrogen (N) fertilizers and its chemical form may influence the activity of P mineralizing enzymes, but how this interaction operates under field conditions in a soil with high P ...
Ingeborg F. Pedersen +3 more
wiley +1 more source