Results 91 to 100 of about 903 (153)

Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis

eLife, 2019
Many eukaryotic proteins regulating phosphate (Pi) homeostasis contain SPX domains that are receptors for inositol pyrophosphates (PP-InsP), suggesting that PP-InsPs may regulate Pi homeostasis.
Jinsheng Zhu, Kelvin Lau, Robert Puschmann, Robert K Harmel, Youjun Zhang, Verena Pries, Philipp Gaugler, Larissa Broger, Amit K Dutta, Henning J Jessen, Gabriel Schaaf, Alisdair R Fernie, Ludwig A Hothorn, Dorothea Fiedler, Michael Hothorn   +14 more
doaj   +1 more source

Science: Pathogenic fungi exploit plant phosphate sensing via Nudix hydrolase effectors

Advanced Agrochem
Inorganic phosphate (Pi) homeostasis in plants is regulated by inositol pyrophosphates (PP-InsPs), which mediate phosphate starvation responses. While beneficial microorganisms, such as arbuscular mycorrhizal fungi, contribute to phosphate uptake ...
Yi-Xuan Fu, Ying Ye
doaj   +1 more source

Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis. [PDF]

Nat Commun, 2021
Ried MK, Wild R, Zhu J, Pipercevic J, Sturm K, Broger L, Harmel RK, Abriata LA, Hothorn LA, Fiedler D, Hiller S, Hothorn M.   +11 more
europepmc   +1 more source

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

Nature Communications
Inositol pyrophosphates (PP-InsPs) are eukaryotic nutrient messengers. The N-terminal kinase domain of diphosphoinositol pentakisphosphate kinase (PPIP5K) generates the messenger 1,5-InsP8, the C-terminal phosphatase domain catalyzes PP-InsP breakdown ...
Pierre Raia, Kitaik Lee, Simon M. Bartsch, Felix Rico-Resendiz, Daniela Portugal-Calisto, Oscar Vadas, Vikram Govind Panse, Dorothea Fiedler, Michael Hothorn   +8 more
doaj   +1 more source

Inositol pyrophosphates in cell death and life [PDF]

Cell Cycle, 2011
Michael A, Koldobskiy, Solomon H, Snyder
openaire   +2 more sources

Inositol pyrophosphate catabolism by three families of phosphatases regulates plant growth and development.

PLoS Genetics
Inositol pyrophosphates (PP-InsPs) are nutrient messengers whose cellular levels are precisely regulated. Diphosphoinositol pentakisphosphate kinases (PPIP5Ks) generate the active signaling molecule 1,5-InsP8.
Florian Laurent, Simon M Bartsch, Anuj Shukla, Felix Rico-Resendiz, Daniel Couto, Christelle Fuchs, Joël Nicolet, Sylvain Loubéry, Henning J Jessen, Dorothea Fiedler, Michael Hothorn   +10 more
doaj   +1 more source

Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. [PDF]

Mol Cell, 2020
Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH.   +13 more
europepmc   +1 more source

Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3' processing and transcription termination. [PDF]

Nucleic Acids Res, 2019
Sanchez AM, Garg A, Shuman S, Schwer B.
europepmc   +1 more source

NUDIX hydrolases target specific inositol pyrophosphates and regulate phosphate homeostasis and bacterial pathogen susceptibility in Arabidopsis. [PDF]

J Integr Plant Biol
Schneider R, Lami K, Prucker I, Stolze SC, Strauß A, Schmidt JM, Bartsch SM, Langenbach K, Lange E, Ritter K, Furkert D, Faiß N, Kumar S, Shamim Hasan M, Makris A, Krusenbaum L, Wege S, Belay YZ, Kriescher S, The J, Harings M, Grundler FMW, Ried-Lasi MK, Schoof H, Gaugler P, Kamleitner M, Fiedler D, Nakagami H, Giehl RFH, Lahaye T, Bhattacharjee S, Jessen HJ, Gaugler V, Schaaf G.   +33 more
europepmc   +1 more source

Correction for Rao et al., Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. [PDF]

Proc Natl Acad Sci U S A, 2020
europepmc   +1 more source