Results 131 to 140 of about 2,351 (231)

Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs. [PDF]

Chem Sci, 2021
Hostachy S, Utesch T, Franke K, Dornan GL, Furkert D, Türkaydin B, Haucke V, Sun H, Fiedler D.   +8 more
europepmc   +1 more source

Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis

eLife, 2019
Many eukaryotic proteins regulating phosphate (Pi) homeostasis contain SPX domains that are receptors for inositol pyrophosphates (PP-InsP), suggesting that PP-InsPs may regulate Pi homeostasis.
Jinsheng Zhu, Kelvin Lau, Robert Puschmann, Robert K Harmel, Youjun Zhang, Verena Pries, Philipp Gaugler, Larissa Broger, Amit K Dutta, Henning J Jessen, Gabriel Schaaf, Alisdair R Fernie, Ludwig A Hothorn, Dorothea Fiedler, Michael Hothorn   +14 more
doaj   +1 more source

Neutrophil Spontaneous Death Is Mediated by Down-Regulation of Autocrine Signaling through GPCR, PI3K\(\gamma\), ROS, and actin [PDF]

, 2014
Neutrophil spontaneous apoptosis plays a crucial role in neutrophil homeostasis and the resolution of inflammation. We previously established Akt deactivation as a key mediator of this tightly regulated cellular death program. Nevertheless, the molecular
Loison, Fabien, Luo, Hongbo, Xu, Yuanfu
core   +1 more source

Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis [PDF]

, 2018
Jinsheng Zhu, Kelvin Lau, Robert K. Harmel, Robert Puschmann, Larissa Broger, Amit K. Dutta, Henning J. Jessen, Ludwig A. Hothorn, Dorothea Fiedler, Michael Hothorn   +9 more
openalex   +1 more source

Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling

, 2023
Ji Qi, Weiwei Cheng, Zhe Gao, Yuanyuan Chen, Megan L. Shipton, David Furkert, Alfred C. Chin, Andrew M. Riley, Dorothea Fiedler, Barry V. L. Potter, Chenglai Fu   +10 more
openalex   +1 more source

Mecanismos de percepción y de respuesta a bajas temperaturas en Saccharomyces cerevisiae [PDF]

, 2014
A lo largo de los años, la levadura S. cerevisiae se ha convertido en organismo modelo tanto en la industria, como en el campo de la investigación básica, debido a sus características metabólicas y su fácil manipulación. Es conocido que, cuando la célula
Córcoles Sáez, Isaac
core  

Genetic suppressor screen identifies Tgp1 (glycerophosphocholine transporter), Kcs1 (IP ₆ kinase), and Plc1 (phospholipase C) as determinants of inositol pyrophosphate toxicosis in fission yeast

, 2023
Lauren Bednor, Ana M. Sánchez, Angad Garg, Stewart Shuman, Beate Schwer   +4 more
openalex   +1 more source

Calcium-binding capacity of organic and inorganic ortho- and polyphosphates [PDF]

The aim of this research was to determine the calcium-binding capacity of inorganic and organic ortho- and polyphosphates. This calcium-binding capacity can be used to influence the stability of, for example, casein micelles in dairy systems.
Hooijdonk, A.C.M., van, Kort, E.J.P., de, Linden, E., van der, Minor, M., Snoeren, T.H.M.   +4 more
core   +2 more sources

Science: Pathogenic fungi exploit plant phosphate sensing via Nudix hydrolase effectors

Advanced Agrochem
Inorganic phosphate (Pi) homeostasis in plants is regulated by inositol pyrophosphates (PP-InsPs), which mediate phosphate starvation responses. While beneficial microorganisms, such as arbuscular mycorrhizal fungi, contribute to phosphate uptake ...
Yi-Xuan Fu, Ying Ye
doaj   +1 more source

Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues [PDF]

, 2022
Danye Qiu, Chunfang Gu, Guizhen Liu, Kevin Ritter, Verena B. Eisenbeis, Tamara Bittner, Artiom Gruzdev, Lea Seidel, Bertram Bengsch, Stephen B. Shears, Henning J. Jessen   +10 more
openalex   +1 more source