Results 201 to 210 of about 1,485 (248)

Detection of Inositol and Inositol Diphosphate on Paper Chromatograms

Nature, 1958
A COLOUR reaction, known as Scherer's test, is extensively used as a specific, qualitative test for inositol. It is based on the formation of the coloured alkaline earth metal salt (usually calcium salt) of rhodizonic acid on the oxidation of inositol with concentrated nitric acid1,2.
Y, NAGAI, Y, KIMURA
openaire   +2 more sources

Inositol treatment raises CSF inositol levels

Brain Research, 1993
Inositol is a key precursor for synthesis of phosphatidylinositol in a major second messenger signalling system. It is biologically active in syndromes such as respiratory distress syndrome but has been thought to be excluded from CNS by the blood-brain barrier.
J, Levine, A, Rapaport, L, Lev, Y, Bersudsky, O, Kofman, R H, Belmaker, J, Shapiro, G, Agam   +7 more
openaire   +2 more sources

Configuration of Inositol Phosphate in Liver Phosphatidyl Inositol

Nature, 1960
THE hydrolysis of synthetic glycerol 1-(inositol 2-phosphate)1,2 has recently been compared with that of the glycerylphosphoryl inositol isolated from hydrolysates of liver phosphatidyl inositol3. The results suggest that the phosphate group in the original lipid is attached to the 1- or 2-hydroxyl of the myoinositol.
J N, HAWTHORNE, P, KEMP, R B, ELLIS
openaire   +2 more sources

Cerebral Lithium, Inositol and Inositol Monophosphates

Pharmacology & Toxicology, 1991
Abstract:Cerebral regional inositol, inositol‐1‐phosphate (InslP), and inositol‐4‐phosphate (Ins4P), intermediates in phosphoinositide (PI) cycle, and brain lithium levels were studied in male HamWistar rats 24 hr after an intraperitoneal injection of a single dose (2, 5–1. mEq./kg) of LiCl.
openaire   +2 more sources

A bioautographic method for the identification of inositol and inositol phosphate

Analytical Biochemistry, 1962
Abstract A bioautographic method, utilizing Saccharomyces carlsbergensis strain 4228, was shown to be capable of detecting and distinguishing between myoinositol, myoinositol 2-phosphate, and other derivatives of myoinositol. The method was shown to respond to as little as 1 μg inositol and is effective even in the presence of lipid hydrolyzates.
openaire   +2 more sources

Metabolism and Function of myo-Inositol and Inositol Phospholipids

Annual Review of Nutrition, 1986
Alterations in the level of dietary inositol can significantly influence the concentration of free inositol and inositol-containing phospholipid in the circulation and in selected mammalian tissues and cells. The 1-stearoyl 2-arachidonyl molecular species that commonly predominates in cellular phosphoinositides may be of considerable importance for the
openaire   +2 more sources

INOSITOL PHOSPHATE BIOCHEMISTRY

Annual Review of Biochemistry, 1992
PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 C ONVENTIONAL PHOSPHA TIDYLIN OSITOLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 PHOSPHOLIPASE C . . . . . . . . . .
openaire   +2 more sources

Antagonistic Effect of Inositol Pentakisphosphate on Inositol Triphosphate Receptors

Biochemical and Biophysical Research Communications, 1996
We present evidence that inositol 1,3,4,5,6-pentakisphosphate acts as an antagonist of inositol triphosphate receptors in vitro by dampening the activity of Ca(2+)-mobilizing inositol phosphates. This antagonism bears physiological significance as cells maintain substantial quantities of this phosphoinositol in the cytosol, especially during cell ...
P J, Lu, W R, Shieh, C S, Chen
openaire   +2 more sources

The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate

Nature, 1994
Activation of intracellular Ca2+ channels by inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) represents the initial Ca2+ mobilization step in response to many extracellular signals. Here we report that Ins(1,4,5)P3-induced channel activation in permeabilized hepatocytes is followed by a time-dependent inactivation, which is a direct consequence of ligand ...
G, Hajnóczky, A P, Thomas
openaire   +2 more sources

Multitarget Activities of Inositol and Inositol Hexakisphosphate

2020
Multiple health beneficial effects have been shown for inositol hexakisphosphate (IP6) and its parent compound myo-inositol (Ins) in animal and human studies. However, the most striking is their consistent and reproducible anticancer effect, actively investigated and demonstrated in various experimental models during the last decades.
openaire   +1 more source