Results 201 to 210 of about 1,468 (246)
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Configuration of Inositol Phosphate in Liver Phosphatidyl Inositol
Nature, 1960THE hydrolysis of synthetic glycerol 1-(inositol 2-phosphate)1,2 has recently been compared with that of the glycerylphosphoryl inositol isolated from hydrolysates of liver phosphatidyl inositol3. The results suggest that the phosphate group in the original lipid is attached to the 1- or 2-hydroxyl of the myoinositol.
J N, HAWTHORNE, P, KEMP, R B, ELLIS
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Cerebral Lithium, Inositol and Inositol Monophosphates
Pharmacology & Toxicology, 1991Abstract:Cerebral regional inositol, inositol‐1‐phosphate (InslP), and inositol‐4‐phosphate (Ins4P), intermediates in phosphoinositide (PI) cycle, and brain lithium levels were studied in male HamWistar rats 24 hr after an intraperitoneal injection of a single dose (2, 5–1. mEq./kg) of LiCl.
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A bioautographic method for the identification of inositol and inositol phosphate
Analytical Biochemistry, 1962Abstract A bioautographic method, utilizing Saccharomyces carlsbergensis strain 4228, was shown to be capable of detecting and distinguishing between myoinositol, myoinositol 2-phosphate, and other derivatives of myoinositol. The method was shown to respond to as little as 1 μg inositol and is effective even in the presence of lipid hydrolyzates.
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Metabolism and Function of myo-Inositol and Inositol Phospholipids
Annual Review of Nutrition, 1986Alterations in the level of dietary inositol can significantly influence the concentration of free inositol and inositol-containing phospholipid in the circulation and in selected mammalian tissues and cells. The 1-stearoyl 2-arachidonyl molecular species that commonly predominates in cellular phosphoinositides may be of considerable importance for the
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INOSITOL PHOSPHATE BIOCHEMISTRY
Annual Review of Biochemistry, 1992PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 C ONVENTIONAL PHOSPHA TIDYLIN OSITOLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 PHOSPHOLIPASE C . . . . . . . . . .
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Antagonistic Effect of Inositol Pentakisphosphate on Inositol Triphosphate Receptors
Biochemical and Biophysical Research Communications, 1996We present evidence that inositol 1,3,4,5,6-pentakisphosphate acts as an antagonist of inositol triphosphate receptors in vitro by dampening the activity of Ca(2+)-mobilizing inositol phosphates. This antagonism bears physiological significance as cells maintain substantial quantities of this phosphoinositol in the cytosol, especially during cell ...
P J, Lu, W R, Shieh, C S, Chen
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The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate
Nature, 1994Activation of intracellular Ca2+ channels by inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) represents the initial Ca2+ mobilization step in response to many extracellular signals. Here we report that Ins(1,4,5)P3-induced channel activation in permeabilized hepatocytes is followed by a time-dependent inactivation, which is a direct consequence of ligand ...
G, Hajnóczky, A P, Thomas
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Multitarget Activities of Inositol and Inositol Hexakisphosphate
2020Multiple health beneficial effects have been shown for inositol hexakisphosphate (IP6) and its parent compound myo-inositol (Ins) in animal and human studies. However, the most striking is their consistent and reproducible anticancer effect, actively investigated and demonstrated in various experimental models during the last decades.
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The metabolism and functions of inositol pentakisphosphate and inositol hexakisphosphate
Biochemical Society Transactions, 1989D, Carpenter +5 more
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