Results 31 to 40 of about 1,536 (249)
Beilstein Journal of Organic Chemistry, 2016 Efficient routes were developed for the diastereoselective synthesis of new O-alkylated and C-branched inositols and their corresponding fluoro analogues.
Charlotte Collet +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2016 The intramolecular aldol condensation of aldohexos-5-ulose derivatives of the D-xylo and L-ribo stereoseries has been studied. Only one of the four possible inososes was isolated from both stereoseries in reasonable yields (30–38%). The results obtained,
Felicia D’Andrea +3 more
doaj +1 more source
Journal of Lipid Research, 1960 T h e dried crystals melted with decomposition a t about 215”. The substance is probably an organic acid but we have not yet had time to examine it thoroughly.” (1) In this modest way inositol seems to have made its first appearance as a lipid constituent.
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte +6 more
wiley +1 more source
Акушерство, гинекология и репродукцияAn important factor of secondary male infertility is deficiency of vitamins and microelements. In the present work, a set of studies on myoinositol (MI), D-chiroinositol (DCI), their synergists (folates, manganese ions) in maintaining gametocyte ...
O. A. Gromova +2 more
doaj +1 more source
Journal of Ovarian Research, 2019 Background Polycystic ovarian syndrome (PCOS) is a highly variable syndrome and one of the most common female endocrine disorders. Although the association inositols-glucomannan may represent a good therapeutic strategy in the treatment of PCOS women ...
Jacopo Troisi +10 more
doaj +1 more source
Stereometric Molecular Engineering for Ultra‐Stable Aqueous Zinc‐Ion Batteries
Advanced Functional Materials, EarlyView.Stereochemical configuration of molecular additives greatly influences interfacial adsorption at the Zn surface. The optimal tilted dual‐anchored adsorption geometry of myo‐inositol constructs a water‐deficient interface and regulates the solvation structure.
Cunxin Liu +4 more
wiley +1 more source